Gross and microscopic criteria are morphologic and thus subjectivity abounds for the pathologist in the diagnosis of benign and malignant melanocytic proliferations [1]. The state-of-the-art criteria, often touted to be definitive, delineates between benign and malignant conditions clinically and histopathologically. This issue becomes murky, however, when the same criteria, on occasion, are pr...

Skin cancer is one of the most common cancers, and its early detection can have a huge impact on outcomes. Deep learning, especially convolutional neural networks, perform well in processing massive amounts data, image data classifying skin cancer. In this paper, networks are mainly used to diagnose classify 7 types lesions, including melanoma, basal cell carcinoma, melanocytic nevus, actinic k...

More and more genetic metabolic abnormalities are now known to cause cancer, which is typically fatal. Any particular body part may become infected by cancerous cells, can be One of the most prevalent types cancer skin spreading worldwide.The primary subtypes squamous basal cell carcinomas, as well melanoma, clinically aggressive accounts for majority fatalities. Screening so crucial.Deep Learn...

AIMS To investigate the immunoreactivity of a range of melanocytic lesions, both benign and malignant, with the monoclonal antibody VS38. This was recently described as a marker of reactive/neoplastic plasma cells and, therefore, is useful in the diagnosis of plasmacytoma/myeloma and lymphomas with plasmacytic differentiation. This study was prompted by the recent observation that a plasmacytoi...

Fibroepithelioma of Pinkus is considered to be a rare variant of basal cell carcinoma with well-defined histopathological features. Clinical diagnosis often requires differentiation from benign lesions such as acrochordon, intradermal melanocytic nevus, neurofibroma, seborrheic keratosis, and even malignant lesions such as amelanotic melanoma. Dermoscopy of this type of lesion is not extensivel...

Congenital melanocytic nevi (CMN) are benign proliferations of cutaneous melanocytes clinically apparent at birth or within the first postnatal weeks (Walton et al., 1976). At least 2.5% of white infants are noted to have some type of pigmented lesion at birth, but only 1% have biopsy-confirmed nevocellular nevi (Walton et al., 1976). Prevalence of CMN ranges from 0.2% to 2.7% in lesions less t...

Halo nevus is a benign melanocytic nevus that is surrounded by a hypopigmented zone. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Although the mechanism for developing the depigmentation around nevus spilus is uncertain an immunologic process may be responsible for the finding of inflammatory infiltrates of...

It has been demonstrated that dermoscopic monitoring of melanocytic lesions allows for the recognition of melanoma in early stages while minimizing the excision of benign lesions. However, it is still pending to determine the real impact of digital follow-up in the clinical management of pigmented lesions. To assess the evidence of follow-up of melanocytic skin lesions with digital dermoscopy i...

PurposeTo study the feasibility and diagnostic value of vascular imaging using optical coherence tomography (OCT)-angiography (OCTA) melanocytic lesions conjunctiva iris.DesignCross-sectional study.MethodsTwenty-five patients with an untreated conjunctival lesion (5 melanoma, 13 nevus, 7 primary acquired melanosis [PAM]) 52 iris (10 42 nevus) were included. Patients imaged a commercially availa...

Dermatoscopy is a method of in vivo evaluation of the structures within the epidermis and dermis. Currently, it may be the most precise pre-surgical method of diagnosing melanocytic lesions. Diagnostic errors may result in unnecessary removal of benign lesions or what is even worse, they can cause early and very early melanomas to be overlooked. Errors in assessment of dermatoscopy can be divid...