In the present study, we have investigated the effects of IL-4 on the proliferation and differentiation of leukemic and normal human B cell precursors (BCP). We have demonstrated that IL-4 significantly inhibited spontaneous [3H]thymidine ([3H]-TdR) incorporation by leukemic blasts from some B lineage acute lymphoblastic leukemia (BCP-ALL) patients (8 of 14). Furthermore, IL-4 was found to supp...

Recently a submicron particle of biphasic calcium phosphate ceramic (BCP) with through-hole (donut-shaped BCP (d-BCP)) was developed for improving the osteoconductivity. This study was performed to examine the usefulness of d-BCP for the delivery of osteoinductive rhBMP2 and the effectiveness on cranial bone regeneration. The d-BCP was soaked in rhBMP2 solution and then freeze-dried. Scanning e...

Basic calcium phosphate (BCP) crystals are associated with severe osteoarthritis and acute periarticular inflammation. Three main forms of BCP crystals have been identified from pathological tissues: octacalcium phosphate, carbonate-substituted apatite, and hydroxyapatite. We investigated the proinflammatory effects of these BCP crystals in vitro with special regard to the involvement of the NL...

BACKGROUND The association between hepatitis B virus (HBV) mutations and hepatocarcinogenesis remains controversial because of conflicting data in the literature. We conducted a meta-analysis of case-control and cohort studies to examine HBV PreS, enhancer II (EnhII), basal core promoter (BCP), and precore mutations in relation to the risk of hepatocellular carcinoma (HCC). METHODS We searche...

BACKGROUND Various studies have reported that the administration of adenosine (ADO) in cardioplegia reduces myocardial ischemic injury, but this timing may not utilize ADO's potential against myocardial reperfusion injury. This study tested the hypothesis that ADO-supplemented blood cardioplegia (BCP) or ADO administered during reperfusion reduces postischemic dysfunction after severe regional ...

The kinetics of the reactions between [Ni(bipy)(COD)] and bicyclopropylidene (bcp), dicyclopropylacetylene (dcpa) 1,4-dimethoxy-2-butyne (dmbu) were investigated using stopped-flow techniques. Similar to previous studies results support an associative mechanism (activation parameters for bcp: ΔH#=46±2 kJ ⋅ mol−1 ΔS#=−69±8 J K−1) therefore allowed postulate a more general reaction pathway. produ...

SELF-ASSEMBLY OF BLOCK COPOLYMERS BYSOLVENT VAPOR ANNEALING, MECHANISM ANDLITHOGRAPHIC APPLICATIONS FEBRUARY 2014XIAODAN GUB.S., NANJING UNIVERSITYM.S., UNIVERSITY OF MASSACHUSETTS AMHERSTPh.D., UNIVERSITY OF MASSACHUSETTS AMHERSTDirected by: Professor THOMAS P. RUSSELL Block copolymers (BCP) are a unique class of polymers, which can self-assembleinto ordered mic...

Non-clausal refinement of Boolean Constraint Propagation inference procedure for classical logic, called P-BCP, is introduced within a new knowledge representational formalism of polarized formulas. P-BCP is a sound, incomplete, and linear-time inference procedure. It is shown that P-BCP can be adopted for tractable reasoning in a number of non-classical logics (including some modal and finitel...

This study compares a traditional agricultural approach to minimise N pollution of groundwater (incorporation of crop residues) with applications of small amounts of biodiesel co-product (BCP) to arable soils. Loss of N from soil to the aqueous phase was shown to be greatly reduced in the laboratory, mainly by decreasing concentrations of dissolved nitrate-N. Increases in soil microbial biomass...

Radiographs and synovial fluids from 66 knees representing 59 patients with symptomatic osteoarthritis were evaluated to determine the pattern of radiographic abnormalities associated with basic calcium phosphate (BCP), calcium pyrophosphate dihydrate (CPPD), or both crystals together. Crystals were found in 71% of fluids. In general, CPPD crystals correlated with patient age, while BCP crystal...