نتایج جستجو برای: bc1
تعداد نتایج: 1088 فیلتر نتایج به سال:
Detection of cellular expression of long noncoding RNAs (lncRNAs) was elusive due to the ambiguity of exposure of their reactive sequences associated with their secondary/tertiary structures and dynamic binding of proteins around lncRNAs. Herein, we developed graphene-based detection techniques exploiting the quenching capability of graphene oxide (GO) flakes for fluorescent dye (FAM)-labeled s...
A previous phenotypic screen by GSK identified 2-(quinolin-4-yloxy)acetamides as potent growth inhibitors of Mycobacterium tuberculosis (Mtb). We report the results of a preliminary structure-activity relationship (SAR) study of the compound class which has yielded more potent inhibitors. An Mtb cytochrome bd oxidase deletion mutant (cydKO) was found to be hypersensitive to most members of the ...
In 2001, Hainan Sugarcane Breeding Farm bred identified as BC1 hybrid strains of Erianthus real sugar cane for the first time. Fuzzy comprehensive evaluation method in Reference [1] studied and analyzed two strains of sugar cane major economic traits of Erianthus hybrids BC1 17 to have determined it is the fine lines. Fuzzy comprehensive evaluation method, mainly relying on fuzzy matrix, has a ...
Complex III (cytochrome bc1 particle; ubiquinol:ferricytochrome c oxidoreductase, EC 1.10.2.2) was purified from beef heart mitochondria by a combination of hydrophobic interaction and affinity chromatography. By washing the complex with detergent on the hydrophobic interaction column, phospholipids were effectively depleted; 7 mol of cardiolipin per mol of cytochrome c1 was retained in the fin...
Better antibiotics capable of killing multi-drug-resistant Mycobacterium tuberculosis are urgently needed. Despite extensive drug discovery efforts, only a few promising candidates are on the horizon and alternative screening protocols are required. Here, by testing a panel of FDA-approved drugs in a host cell-based assay, we show that the blockbuster drug lansoprazole (Prevacid), a gastric pro...
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in cats, the gold standard criterion for cysts. These cysts ...
East Africa highland banana (Musa spp., AAA-EAHB) or ‘matooke’ is a major staple crop grown for food and sale by smallholder farmers in Uganda. Banana yields in farmers’ fi elds average 15 t/ha fresh weight (FW), and have remained small compared with yields of 60 to 70 t/ha/yr achieved at a research station with fertilizer application (Tushemereirwe et al., 2001; Smithson et al., 2001). Low ban...
B et te r C ro ps /V ol . 9 9 (2 01 5, N o. 1 ) Abbreviations and notes: N = nitrogen; P = phosphorus; K = potassium; S = sulfur; Cu = copper; Fe = iron; Mn = manganese; Mo = molybdenum; Zn = zinc. Sustainable crop production is essential to a healthy and adequate food supply. At fi rst glance, a healthy crop reveals only the above ground plant; the roots that support the visible plant are seld...
Gossypium hirsutum L. is the predominant cotton of commerce and all cultivars of this species are susceptible to the reniform nematode, Rotylenchulus reniformis. To introgress resistance to R. reniformis into the tetraploid 2(AD1) G. hirsutum, a resistant diploid A2-genome Gossypium arboreum accession (A2190) was crossed with a hexaploid 2((AD1)D4) bridging line (G 371) to obtain a tetraploid t...
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