نتایج جستجو برای: base sequence
تعداد نتایج: 628559 فیلتر نتایج به سال:
A phylogenetic method is a consistent estimator of phylogeny if and only if it is guaranteed to give the correct tree, given that sufficient (possibly infinite) independent data are examined. The following methods are examined for consistency: UPGMA (unweighted pair-group method, averages), NJ (neighbor joining), MF (modified Farris), and P (parsimony). A two-parameter model of nucleotide seque...
This paper explores the connection between the size of the spectral coefficients of a nucleotide or any other symbolic sequence and the distribution of nucleotides along certain subsequences. It explains the connection between the nucleotide distribution and the size of the spectral coefficients, and gives a necessary and sufficient condition for a coefficient to have a prescribed magnitude. Fu...
Title RNA-seq count data employed in the vignette of the tweeDEseq package Description RNA-seq count data from Pickrell et al. (2010) employed to illustrate the use of the Poisson-Tweedie family of distributions with the tweeDEseq package.
A basic task in the analysis of count data from RNA-Seq is the detection of differentially expressed genes. The count data are presented as a table which reports, for each sample, the number of reads that have been assigned to a gene. Analogous analyses also arise for other assay types, such as comparative ChIP-Seq. The package DESeq provides methods to test for differential expression by use o...
Statistical tests for detecting mosaic structure or recombination among nucleotide sequences usually rely on identifying a pattern or a signal that would be unlikely to appear under clonal reproduction. Dozens of such tests have been described, but many are hampered by long running times, confounding of selection and recombination, and/or inability to isolate the mosaic-producing event. We intr...
The Drosophila obscura species group has served as an important model system in many evolutionary and population genetic studies. Despite the amount of study this group has received, some phylogenetic relationships remain unclear. While individual analysis of different nuclear, mitochondrial, allozyme, restriction fragment, and morphological data partitions are able to discern relationships amo...
It is demonstrated that the shapes and magnitudes of DNA writhe can be precisely manipulated solely through maneuvering the nucleotide sequence of DNA and without the assistance of topoisomerases.
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