Neoplastic lesions of the skin are among the most common human malignancies. They originate from different skin tissues and structures such as:  epidermis  skin appendages (hair follicles, sebaceous glands, eccrine sweat glands, apocrine sweat glands)  pigment cells (melanocytes)  mesenchymal structures (fibrous tissue, fatty tissue, blood and lymphatic vessels, muscles)  nerves and APUD c...

nodules that reside within the dermis and frequently demonstrate epidermal attachment. Multifocal lobules of varying size and shape exhibit peripheral palisading and central haphazard array of cells.The entire tumor demonstrates an expansile growth pattern. Cystic degeneration or central necrosis may be prominent. Although similar to the nodular variant, micronodular basal cell carcinoma is com...

8. Makker R, Ramesh V. On the diagnosis of facial granulomatous dermatoses of obscure origin. International Journal of Dermatology. 2005;44:606-9. 9. Helm KF, Menz J, Gibson LE, Dicken CH. A clinical and histopathologic study of granulomatous rosacea. J Am Acad Dermatol. 1991;25:1038-43. 10. Cribier B, Lieber-Mbomeyo A, Lipsker D. Clinical and histological study of a case of facial Afro-Caribbe...

Basal cell carcinoma is the most common skin cancer in the Caucasian population. The cancer arises in sun exposed areas of the skin. The incidence of morbidity is high and it is still growing. The metastatic rate is low, but the enlarging tumor may cause severe tissue disfigurement and a poor cosmetic outcome. The diagnosis is usually clinical but there are many subtypes of this carcinoma and c...

Basal cell carcinoma (BCC) is the most common type of skin cancer (75% to 80%) and the most common of all cancers (more than one out of every three new cancers). Seventy to eighty percent of BBC occurs in the head and neck region, followed by the trunk (about 25%), and penis, vulva, or perianal skin (about 5%). It is more common in light-skinned individuals (type 1 or type 2 skin) with a family...

A. Environmental factors 1. Non-Ionizing Radiation – Ultraviolet (UVA & UVB) Two wavelength “types” of UV reach the earth’s surface – UVA (320-400nm) and UVB (290-320nm). Most of the UVB and all UVC are filtered by stratospheric ozone. UVA was initially thought to be noncarcinogenic, but is now thought to be a potent co-carcinogen with UVB. Recently, high dose UVA (as found in tanning beds) has...

OBJECTIVE The purpose of this study is to review our series of metastatic basal cell carcinomas of the head and neck. STUDY DESIGN A retrospective review was conducted for this study. METHODS All cases of documented metastatic basal cell carcinomas arising from a primary within the head and neck region and presenting for treatment to one of the authors (Y.D.) were included in this review. ...

Basal Cell Carcinoma (BCC) is the most common malignant tumour of the skin. It is also the most common cancer in humans in some countries. BCC is malignant neoplasm derived from nonkeratinizing cells originating in the basal layer of the epidermis. The histology of the tumour and the surrounding stroma is characteristic. Basal cell carcinoma was first described in 1824 by Jacob who called it "u...

8. Makker R, Ramesh V. On the diagnosis of facial granulomatous dermatoses of obscure origin. International Journal of Dermatology. 2005;44:606-9. 9. Helm KF, Menz J, Gibson LE, Dicken CH. A clinical and histopathologic study of granulomatous rosacea. J Am Acad Dermatol. 1991;25:1038-43. 10. Cribier B, Lieber-Mbomeyo A, Lipsker D. Clinical and histological study of a case of facial Afro-Caribbe...