Contributors: Dr Dominic Slowie, Medical School, Newcastle upon Tyne; Shee Lippell, University of Plymouth Business School; Jill Dales; Peter Campion, University of Hull; Sarah Gull; Amanda Howe, Institute of Health University of East Anglia; Gill McConnell, University of Edinburgh; Eva Doherty, Royal College of Surgeons in Ireland; Penny Morris, University of Leeds; Rafey Faruqui, Imperial Col...

Judy Davies is Senior Tissue Viability Research Coordinator, Richard Bull is Consultant Dermatologist and Ina Farrelly is Senior Podiatrist at East London Wound Healing Centre, Mile End Hospital, Tower Hamlets Primary Care Trust, London and Melanie Wakelin is Statistician at the Centre for Health Sciences, Barts and the London Queen Mary’s School of Medicine and Dentistry, London When treating ...

Hemoglobin Barts hydrops fetalis (homozygous a-thalassemia) results from deletion of all 4 a-globin genes. It was previously considered a universally fatal condition; however,with recent advances in prenatal care and the availability of intrauterine blood transfusions, an increasing number of patients are now surviving into adulthood. Similar to patients with transfusion-dependent thalassemia d...

OBJECTIVE Studies indicate a limited understanding of dementia and its associated symptoms, causes and consequences among South Asian older adults. As a consequence, fewer people from this ethnic group receive a diagnosis of dementia. The aim of this study was to adapt the previously designed Barts Explanatory Model Inventory Checklist (BEMI-C), a tool designed to elicit perceptions of mental i...

The project is an interdisciplinary collaboration involving a diverse team of senior researchers in the School of Electronic Engineering and Computer Science (EECS) and clinical academics from the Barts and the London School of Medicine and Dentistry School (SMD). The team has evolved from previous relevant successful interdisciplinary projects in which members of EECS, and especially the Risk ...

Skeletal muscle dysfunction is associated with derangements in mitochondrial 1 bioenergetics (but not UCP3) in a rodent model of sepsis 2 3 Parjam Zolfaghari, Jane E Carré, Nadeene Parker, Nancy A Curtin, Michael R Duchen, 4 Mervyn Singer. 5 1 Bloomsbury Institute for Intensive Care Medicine, University College London, Cruciform 6 Building, Gower Street, London WC1E 6BT, UK 7 2 National Heart a...

Although we can now identify some nondiabetic suggest that prolonged and possibly permanent remissions individuals who will subsequently develop clinical in the IDDM disease process are as common as progressive insulin-dependent diabetes'melliius (IDDM), our ability P-cell loss leading to clinical DDM. to predict subsequent clinical IDDM is far from perfect. The Barts-Windsor family study proba...

Dr. N.M. Joshi, BSc, MRCP Clinical Research Fellow. Prof. D.S. Rampton, DPhil, FRCP. Professor of Clinical Gastroenterology, Centre for Digestive Diseases, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK Patients with inflammatory bowel disease (IBD) are at higher risk of developing Clostridium difficile...

Haemoglobinopathies and different forms of thalassaemias including alpha thalassaemia has been found to be as high as 10% in Eastern India. The alpha globin disorders are less commonly reported because the diagnosis of alpha thalassaemia is usually missed unless in the severe homozygous form or as Hb Barts. But presence of alpha gene has been found in cases of unexplained anaemias and also in s...