Widespread use of various antimicrobial agents resulted in the emergence of bacterial resistance. Mechanisms like direct efflux, formation, and sequestration of metals and drugs in complexes and antiporter pumps are some examples. This investigation aims to investigate the resistance pattern of penicillin-resistant bacterial strains to some physicochemical agents. Sensitivity/resistance pattern...

The spread of bacterial infectious diseases due to the development of resistance to antibiotic drugs in pathogenic bacteria is an emerging global concern. Therefore, the efficacious management and prevention of bacterial infections are major public health challenges. RecA is a pleiotropic recombinase protein that has been demonstrated to be implicated strongly in the bacterial drug resistance, ...

conclusions bacterial resistance against chlorhexidine is increasing. sub-mic doses of chlorhexidine digluconate can stimulate the formation of biofilm strains. materials and methods forty clinical isolates of escherichia coli, salmonella serotypes, staphylococcus. aureus and streptococcus agalactiae (10 isolates for each) were examined for chlorhexidine digluconate effects on biofilm formation...

Background and Objective: Hospitals niche as a source and repository for microbial infections are playing a significant role in the health of hospitalized patients. Bacteria are playing an essential role in human and animal blood infections and meningitis. The prevalence of bacterial agents and their susceptibility patterns are fundamental goals of current research. Materials and Methods: Samp...

Introduction: Bacterial meningitis is still one of the most dangerous infectious diseases and causes serious complications and mortalities in children. The aim of this study was to identify the most common of bacterial agents causing meningitis in children under 10 years old and to detect their resistance to antibiotics in patients who referred to the educational hospital of Hamadan. Materials...

from hygienic and economical point of view, drug therapy and prophylaxy in infectious diseases are of great importance. after the world war ii, a reduction in the efficacy of sulfonamide in the treatment of shigellosis was observed and later on it led to a survey on drug resistance and the way of its transmission. the aim of this survey, during which 100 cases of gram-negative bacteria were ide...

Broad-spectrum disease resistance against two or more types of pathogen species is desirable for crop improvement. In rice, Xanthomonas oryzae pv. oryzae (Xoo), the causal bacteria of rice leaf blight, and Magnaporthe oryzae, the fungal pathogen causing rice blast, are two of the most devastating pathogens. We identified the rice BROAD-SPECTRUM RESISTANCE 1 (BSR1) gene for a BIK1-like receptor-...

Cecropin B is a cationic antimicrobial peptide originally isolated from the diapausing pupae of the giant silk moth, Hylphora cecropia. Cecropin B elicits its antimicrobial effects through disruption of the anionic cell membranes of gram-negative bacteria. Previous work by our laboratory demonstrated that a constitutively expressed cecropin B transgene conferred enhanced resistance to bacterial...