tiation of true dysentery bacilli from allied organisms described and named three species or groups of species of bacilli which though strongly resembling the true dysentery bacilli were not considered by him as causal agents of dysentery; one of these was Bacterium alkalescens. Andrewes described it as a Gram-negative non-motile bacillus which produced acid but no gas in glucose, maltose, mann...

The Mitsuda and Fernandez reactions to bacilli prepared from lesions of human patients and bacilli from infected armadillos were studied in 112 leprosy patients. It was observed that there is no substantial difference when armadillo lepromin is used instead of human lepromin except that a larger induration occurs with the use of the armadillo lepromin in a majority of cases. The number of those...

1. The skin lesions in rabbits and guinea pigs following intradermal injection of tubercle bacilli (5 strains) were greatly increased in size and severity when testicle extract was added to the inoculum. Such enhancement was followed by a more widespread and rapidly progressing disease only when virulent strains were employed. 2. Attempts to suppress the development of skin lesions resulting fr...

In view of the growing interest and increased incidence of tuberculosis in India, it is extremely important to determine the various sources of dissemination of tubercle bacilli. It has been estimated that as many as 40 per cent of cattle are tuberculous in certain parts of England and about 7 per cent of samples of milk in London contain tubercle bacilli. Although milk is generally boiled in I...

Sputum culture for tubercle bacilli on a solid egg medium containing glycerol was compared with culture on a similar medium containing pyruvic acid and no glycerol. Tubercle bacilli from the sputum of five out of 99 patients grew on pyruvic acid medium but not on glycerol medium. The addition of pyruvic acid is therefore essential when an egg medium is used for the cultural diagnosis of tubercu...

The National Institute of Health of Japan, Tokyo (Received for publication, March 30, 1950) Evolutional steps of -nitrogen requirements of bacteria have been set up as follows. N2-N03-NH4-amino nitrogen-amino nitrogen+growth factor. Dysentery bacilli belong to the last step (3, 4, 6). As shown in the preceding report (5), Shigella dysenteriae (Shiga type) belongs to the transition zone between ...

A preceding communication (1) reported the maintenance of fibroblasts from lepromata in serum media for periods of 14 to 34 days. The heavily bacillated macrophages died in situ and deposited their bacilli within the original explants. A relatively low proportion of smaller round cells which sometimes migrated into the plasma, were not sustained by serum media, as had been hoped, and disappeare...

On the basis of our previous observations and related literatures, was assumed tht cholesterol esters of host origin and phthiocerol dimycocerosate of bacterial origin are located as a lipid mixture around the periphery of pathogenic mycobacteria growing in vivo, probably within the phagocytic vacuole of macrophages. To examine the role of such a postulated lipid complex in mycobacterial infect...

The successful use of Bacillus anthracis as a lethal biological weapon has prompted renewed research interest in the development of more effective vaccines against anthrax. The disease consists of three critical components: spore, bacillus, and toxin, elimination of any of which confers at least partial protection against anthrax. Current remedies rely on postexposure antibiotics to eliminate b...