Sinonasal lymphoma is a rare disease with NK/T-cell (NKTC) or B-cell immunophenotype. Previous study revealed the geographic difference in frequency of NKTC lymphoma (NKTCL) and almost constant association with Epstein-Barr virus (EBV) infection. Through review of 41 cases with sinonasal lymphoproliferative diseases registered in the Department of Anatomical Pathology, University of Indonesia d...

Primary central nervous system (PCNSL) lymphoma is an aggressive extranodal non-Hodgkin lymphoma, and most cases are classified as diffuse large B-cell lymphoma (DLBCL) by histology. T-cell/histiocyte-rich large B-cell lymphoma (TCRLBCL) represents a distinct subtype of diffuse large B-cell lymphoma and is characterized by the presence of scattered large neoplastic B-cells in a background of ab...

Received: June 24, 2003. *Correspondence: Fax: 380(44)-2581656; E-mail: [email protected] Abbreviations used: ABC-DLBCL — diffuse large B-cell lymphoma with activated B cell phenotype; BCR — B cell receptor; BL — Burkitt’s lymphoma; DLBCL — diffuse large B-cell lymphoma; GC — germinal center; GC-DLBCL — diffuse large B-cell lymphoma with germinal center phenotype; HL — Hodgkin’s lymphoma...

BACKGROUND Gene expression profiling has successfully identified the prognostic significance of the host response in lymphomas. The aggressive T-cell/histiocyte-rich large B-cell lymphoma and the indolent nodular lymphocyte-predominant Hodgkin's lymphoma are both characterized by a paucity of tumor cells embedded in an overwhelming background. The tumor cells of both lymphomas share several cha...

Chromosomal rearrangements observed in T-cell prolymphocytic leukemia involve the translocation of one T-cell receptor gene to either chromosome 14q32 or Xq28, deregulating the expression of cellular protooncogenes of unknown function, such as TCL1 or its homologue, MTCP1. In the human hematopoietic system, TCL1 expression is predominantly observed in developing B lymphocytes, whereas its overe...

Current cancer diagnosis procedure requires expert knowledge and is time-consuming, which raises the need to build an accurate support system for lymphoma identification classification. Many studies have shown promising results using Machine Learning and, recently, Deep detect malignancy in cells. However, diversity complexity of morphological structure make it a challenging classification prob...

Background: The clinical presentation of non-Hodgkin lymphoma (NHL) varies tremendously depending upon the type of lymphoma and the areas of involvement. NHL can rarely present as an abdominal mass compressing the inferior vena cava. The clinical presentation due to obstruction of inferior vena cava has often been called the inferior vena cava syndrome (IVCS). It can present acutely or chronica...

Introduction: Central mucoepidermoid carcinoma (CMEC) is a rare primary intraosseous bony lesion. The mandible is more commonly affected than the maxilla. CMEC is frequently misdiagnosed radiographically and clinically as a benign odontogenic tumor or cyst. Case Presentation: We present a rare case with a secondary malignant neoplasm. A male patient was initially diagnosed with B-cell non-Hodg...

Proteins of the B-cell lymphoma 2 family are crucial for the regulation of apoptosis. B-cell lymphoma 2-associated X is a pro-apoptotic protein, while B-cell lymphoma 2 protein opposes apoptosis. The influence of 1 microM 2-methoxyestradiol was investigated on the expression levels of these two proteins in MCF-7 cells. 2-Methoxyestradiol exposure did not influence B-cell lymphoma 2 protein expr...