نتایج جستجو برای: b cell epitope

تعداد نتایج: 2302597  

Journal: :novelty in biomedicine 0
mohammad mehdi ranjbar razi vaccine and sera institute, karaj, iran sedigheh nabian department of parasitology, tick and tick-borne diseases center, faculty of veterinary medicine, university of tehran, tehran, iran nayeb ali ahmadi proteomics research center, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, iran khodayar ghorban department of immunology, aja university of medical sciences, tehran, iran alireza sazmand department of agriculture, payame noor university-yazd brancesh, yazad, iran maryam dadmanesh department of infectious diseases, aja university of medical sciences, tehran, iran

background: dermatophagoides farinae and dermatophagoides pteronyssinus are house dust mites (hdm) that they cause severe asthma and allergic symptoms. tropomyosin protein plays an important role in mentioned immune and allergic reactions to hdms. here, tropomyosin protein from dermatophagoides spp. was comprehensively screened in silico for its allergenicity, antigenicity and similarity/conser...

Journal: :Journal of virology 2011
Mattia Bonsignori Kwan-Ki Hwang Xi Chen Chun-Yen Tsao Lynn Morris Elin Gray Dawn J Marshall John A Crump Saidi H Kapiga Noel E Sam Faruk Sinangil Marie Pancera Yang Yongping Baoshan Zhang Jiang Zhu Peter D Kwong Sijy O'Dell John R Mascola Lan Wu Gary J Nabel Sanjay Phogat Michael S Seaman John F Whitesides M Anthony Moody Garnett Kelsoe Xinzhen Yang Joseph Sodroski George M Shaw David C Montefiori Thomas B Kepler Georgia D Tomaras S Munir Alam Hua-Xin Liao Barton F Haynes

V2/V3 conformational epitope antibodies that broadly neutralize HIV-1 (PG9 and PG16) have been recently described. Since an elicitation of previously known broadly neutralizing antibodies has proven elusive, the induction of antibodies with such specificity is an important goal for HIV-1 vaccine development. A critical question is which immunogens and vaccine formulations might be used to trigg...

2016
Hilyatuz Zahroh Ahmad Ma’rup Usman Sumo Friend Tambunan Arli Aditya Parikesit

Meningitis infection is one of the major threats during Hajj season in Mecca. Meningitis vaccines are available, but their uses are limited in some countries due to religious reasons. Furthermore, they only give protection to certain serogroups, not to all types of meningitis-inducing bacteria. Recently, research on epitope-based vaccines has been developed intensively. Such vaccines have poten...

Journal: :Vaccines 2021

Background: The papaya mosaic virus (PapMV) vaccine platform is a rod-shaped nanoparticle made of the recombinant PapMV coat protein (CP) self-assembled around noncoding single-stranded RNA (ssRNA) template. induces innate immunity through stimulation Toll-like receptors (TLR) 7 and 8. display antigen at surface nanoparticle, associated with co-stimulation signal via TLR7/8, ensures strong immu...

2017
Meena Narayanan Raphaela Freidl Margarete Focke-Tejkl Ulrike Baranyi Thomas Wekerle Rudolf Valenta Birgit Linhart

More than 40% of allergic patients suffer from grass pollen allergy. Phl p 1, the major timothy grass pollen allergen, belongs to the cross-reactive group 1 grass pollen allergens that are thought to initiate allergic sensitization to grass pollen. Repeated allergen encounter boosts allergen-specific IgE production and enhances clinical sensitivity in patients. To investigate immunological mech...

2012
Yohan Kim Julia V. Ponomarenko Zhanyang Zhu Dorjee Tamang Peng Wang Jason Greenbaum Claus Lundegaard Alessandro Sette Ole Lund Philip E. Bourne Morten Nielsen Björn Peters

The immune epitope database analysis resource (IEDB-AR: http://tools.iedb.org) is a collection of tools for prediction and analysis of molecular targets of T- and B-cell immune responses (i.e. epitopes). Since its last publication in the NAR webserver issue in 2008, a new generation of peptide:MHC binding and T-cell epitope predictive tools have been added. As validated by different labs and in...

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