PURPOSE Accurate assessment of metastasis in sentinel lymph nodes (SLN) of breast cancer is important but involves a heavy workload for the pathologist. We conducted a multicenter clinical trial in Japan to evaluate a new automated assay system for cytokeratin 19 mRNA, the one-step nucleic acid amplification (OSNA) assay (Sysmex), to detect lymph node metastasis of breast cancer. EXPERIMENTAL...

BACKGROUND Sentinel node biopsy (SNB) has become a standard treatment in staging axillary lymph nodes in early breast cancer. SNB, however, is an invasive procedure and is time-consuming when the sentinel node is analysed intra-operatively. Breast cancer is frequently characterised by increased 2-fluoro-2-deoxy-D-glucose uptake and many studies have shown encouraging results in detecting axilla...

BACKGROUND Carbon nanoparticle suspension, using smooth carbon particles at a diameter of 21 nm added with suspending agents, is a stable suspension of carbon pellets of 150 nm in diameter. It is obviously inclined to the lymphatic system. There were some studies reporting that carbon nanoparticles are considered as superior tracers for sentinel lymph nodes because of their stability and operat...

background & objectives: colon cancer is currently of high incidence and mortality rate. identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. the aim of the present study is to investigate the effect of this factor on the prognosis of the patie...

BACKGROUND: Coexistence of cancer and tuberculosis in axillary lymph nodes is rare. Only seven cases have been reported in the literature. CASE REPORT: We report here a case of infiltrating ductal carcinoma breast metastasizing to the axillary lymph node along with tubercular granuloma in the same lymph node without primary mammary or pulmonary tuberculosis. CONCLUSION: Primary tuberculosis coe...

background: axillary nodal spread is an established prognostic factor in breast cancer. axillary nodal dissection and subsequent pathological examination is considered the gold standard technique of assessing the axilla for metastatic disease. a minimum of ten level i axillary nodes are required to be examined before an axillary specimen can be reliably labeled as disease free. this recommendat...

purpose: to report a uveal metastasis from infiltrative ductal carcinoma of breast. case report: a 45 year old woman with 9 year history of left breast ductal carcinoma and axillary lymph nodes involvement has found soft tissue are right eye uveal metastasis after 5 and 9 years respectively. conclusion: every patient with breast carcinoma should have complete eye examination at least every 6 mo...

Background: Adjuvant radiotherapy in T1-T2 invasive breast carcinoma and 1-3 positive lymph nodes is controversial due to discrepancies in the reported locoregional recurrence risks and survival data. Purpose: This work aims to explore the effectiveness of postoperative radiation therapy in patients with 1-3 positive axillary lymph nodes treated by modified radical mastectomy with systemic chem...