BACKGROUND Autonomic denervation may suppress atrial fibrillation (AF) vulnerability. This study was designed to assess the short- to mid-term effects of botulinum toxin, a cholinergic neurotransmission blocker, on AF inducibility. METHODS AND RESULTS A total of 23 mongrel dogs were studied. The sinus node and atrioventricular node epicardial fat pads were exposed through a right lateral thor...

AIMS/INTRODUCTION Previously, it was observed that long-term ingestion of a probiotic strain Lactobacillus casei Shirota (LcS) ameliorates insulin resistance and glucose intolerance in rats fed a high-fat diet. In the present study, we examined its possible role in the autonomic nervous system during LcS-induced modulations in glucose and lipid metabolism or cardiovascular functions. MATERIAL...

A Kashmiri family with 3 members affected by a congenital sensory and autonomic neuropathy and corneal opacification is described. The 3 affected cases were offspring of consanguinous marriages in two generations; autosomal recessive inheritance is therefore probable. Pain and temperature sensation was lost in the limbs with a resulting mutilating acropathy. Sudomotor function was also impaired...

a 25-year-old afghan male was presented to the emergency department with femoral shaft fracture following fall from the height. the patient was subjected to femoral nerve block and general anesthesia. first try for performing nerve block led to vascular puncture. therefore, the needle was removed and re-inserted 1 cm lateral to first puncture site and dex injected slowly with aspiration check a...

Background and Objective: Pain is one of the most common complications after thyroidectomy. Opioid administration can overcome this complication, however, it has some side effects, including nausea and vomiting. So, the use of local anesthetic instead of opioids is a good alternative. This study was conducted to evaluate and compare the effect of ultrasound-guided superficial cervical plexus bl...

conclusion lumbar medial branch nerve block under ultrasound guidance was associated with high rates of treatment success and excellent treatment outcomes for facet joint pain. it is also feasible and administers no radiation. thus, ultrasound-guided procedures can be used instead of conventional methods. results the success rate was 98% (87/89 blocks), which was due to our use of ultrasound gu...