BACKGROUND Vocal cord sequelae and postoperative hoarseness during general anesthesia are a significant source of morbidity for patients and a source of liability for anesthesiologists. Several risk factors leading to laryngeal injury have been identified in the past. However, whether the quality of tracheal intubation affects their incidence or severity is still unclear. METHODS Eighty patie...

background: increase in intraocular pressure (iop) following tracheal intubation during general anesthesia can be troublesome. we compared the influence of two muscle relaxants, cisatracurium and atracurium, on iop in patients undergoing general anesthesia. methods: this randomized, double-blind, comparative trial was conducted on 90 candidates for elective non-ophthalmic surgery under general ...

BACKGROUND AND OBJECTIVES This experimental study investigated the in vitro and in vivo neuromuscular blockade of rocuronium and atracurium in rats treated with carbamazepine and determined the concentration of cytochrome P450 and b5 reductase in hepatic microsomes. METHODS Rats were treated with carbamazepine (CBZ)--40 mg x kg(-1) by gavage and sacrificed on the eighth day under anesthesia w...

BACKGROUND AND OBJECTIVES Lithium is widely used for the treatment of bipolar disorders and can interact with neuromuscular blockers. There is a controversy about the mechanisms by which it affects neuromuscular transmission and its interaction with neuromuscular blockers. The objective of this study was to evaluate, on the rat diaphragm, the effects of lithium on the muscular response and indi...