results serum estradiol levels tended to have a negative correlation with homeostasis model assessment of insulin resistance (homa-ir) in premenopausal women but not in postmenopausal women. on the other hand, free testosterone levels tended to have a positive correlation with homa-ir in postmenopausal women but not in premenopausal women. serum shbg levels showed significant negative correlati...

BACKGROUND AND PURPOSE Tibolone is a tissue-specific compound that has favorable effects on bone and menopausal symptoms without stimulating endometrium or breast, but lowers concentrations of plasma high-density lipoprotein (HDL) cholesterol (HDLC). This study was designed to determine whether the HDL lowering with tibolone exacerbated common or internal carotid artery atherosclerosis and to e...

BACKGROUND Overt hypothyroidism has been found to be associated with cardiovascular disease. Whether subclinical hypothyroidism and thyroid autoimmunity are also risk factors for cardiovascular disease is controversial. OBJECTIVE To investigate whether subclinical hypothyroidism and thyroid autoimmunity are associated with aortic atherosclerosis and myocardial infarction in postmenopausal wom...

Estrogen replacement therapy (ERT) has been associated with favorable effects on risk factors for atherosclerosis. In observational studies ERT was also suggested to reduce the risk of cardiovascular disease in postmenopausal women, but the cardioprotective role of estrogen has been challenged after negative results in randomized trials. However, the mechanisms of estrogen action in atheroscler...

the purpose of the present study was to compare some biochemical markers of cancer diseases risk between two groups of active and inactive postmenopausal women. for this purpose, 74 postmenopausal women were required to complete baecke questionnaire. they were divided into two groups: active (age: 55.89±4.38 years, height: 156.93±0.05 cm, weight: 63.18±6.50 kg, body fat percentage: 26.25±6.29, ...

Rationale: Postmenopausal atherosclerosis (AS) has for decades been attributed to estrogen deficiency. Although the follicular stimulating hormone (FSH) levels rise sharply in parallel, the direct effect of FSH on AS has never been investigated. In this study, we explored the possible role of FSH in the development of AS. Methods: This was a prospective cohort study of 48 healthy premenopausal ...

background: osteoporosis is the most common metabolic bone disease in postmenopausal women. it seems necessary to determine the factors affecting the adoption of preventive behaviors of osteoporosis in postmenopausal women using the patterns that identify the factors influencing behavior. objectives: to investigate preventive behaviors of osteoporosis in postmenopausal women in fasa, fars provi...

BACKGROUND AND AIM: The sense of taste is a chemical sense which allows everyone to perceive the flavor of what is eaten or drunk. Also, the sense of olfaction is also a chemical sense contributing to the sense of taste to perceive the taste and flavor of food. In the present work, the gustatory and olfactory function in pre- and postmenopausal women and men were studied and compared to each ot...

OBJECTIVES To investigate the relationship between endogenous androgens and body fat distribution in early and late postmenopausal women. MATERIALS AND METHODS We enrolled postmenopausal women consisting of an early group (≤ 5 years since menopause, n = 105) and a late group (≥ 10 years since menopause, n = 107). Each group was subdivided into normal weight (BMI <24 kg/m(2)) group, overweight...