background: il-17 is a major cytokine player in t cell mediated leukocyte associated inflammation. il-17 is also recognized to participate in the pathophysiology of asthma. objective: to determine the role of il-17 in predicting severe asthma. methods: we obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...

INTRODUCTION The role of soluble OX40 ligand (sOX40L) in adult bronchial asthma is unclear. This study aims to determine the serum concentrations of sOX40L in adult patients with bronchial asthma, and discussed its relationship with pulmonary function. MATERIALS AND METHODS We measured the pulmonary function using the spirometer and detected the serum concentrations of sOX40L by enzyme linked...

Obesity as a common health risk is increasing all over the world. The aim of this study was evaluation of standing and sitting positions on spirometric values in obese asthmatic patients, in comparison with normal obese subjects. The study included 49 obese asthmatic patients with mean age of 42.63 years and body mass index of 36.06 kg/m2, and 51 control obese normal subjects with mean age of 3...

BACKGROUND Despite a long-standing recognition, the bronchial hyperresponsiveness (BHR) of airway smooth muscle, in asthmatic and non-asthmatic subjects is still under investigation. OBJECTIVE In order to better understand the mechanism regulating the airway function, some results obtained with cellular physiology techniques are compared, for some non-asthmatic without BHR subjects and other ...

Asthma is a non communicable obstructive lung disease. It condition in which person's airways become inflamed, narrow, swell, and produce extra mucus, making breathing difficult. After being diagnosed with asthma patients not only suffer from physical symptoms but also mental disorders such as prolonged stress, anxiety disorders, depression, PTSD (Post-traumatic stress disorders), fear panic al...

BACKGROUND Hypozincemia could lead to a variety of defects in growth and the immune system, while it seems to be associated with increased rate of asthmatic attacks in children. METHODS This study was performed to assess the serum zinc level in 100 paediatric asthmatic patients in comparison with a control group. RESULTS Mean serum level of zinc in the asthmatic patients was 70.5±22.6 μg/dL...