Background Several studies have been conducted towards the identification of biomarkers for Alzheimer’s disease (AD); however, there are limited biomarker investigating preclinical phase prior to incidence AD. The present study aims identify a multianalyte panel blood associated with overall cognitive function in healthy ageing male population. Method A multiple reaction monitoring (MRM)-based ...

A sex steroid-binding protein (SBP) that binds to 17 b-estradiol with high affinity and moderate capacity was identified in the plasma of female and juvenile of kutum (Rutilus frisii kutum) sampled during the early stage of gonadal maturation in October and prior to spawning in March. Mean maximum specific binding (Bmax) and equilibrium dissociation constant (Kd) of the fish were as follows: In...

changes in dietary electrolyte balance influence the metabolic fate of protein and many amino acids. furthermore, acid-base condition is achieved in part by the alteration of dietary amino acids pattern and quantity. therefore, a trial was conducted in a completely randomized design to evaluate performance, carcass characteristics, plasma electrolyte and uric acid concentrations of 19 and 28-da...

Secretagogues stimulate both secretion and reuptake of surfactant components by pulmonary type II cells as well as enhance surfactant protein A (SP-A) binding. We have evaluated the possibility that the observed increase in SP-A binding is due to the movement of SP-A receptors from an intracellular pool to the plasma membrane. We utilized an anti-idiotypic monoclonal antibody, A2R, which recogn...