background: in leishmaniasis, some drugs prescribed for treatment have toxic ef-fects and there are reports about drug resistance in some countries. due to this fact, using herbal drugs such as artemisinin with good efficacy and low toxic effect might be suitable. methods: we evaluated the apoptotic effect of artemisinin on leishmania major in vitro and the antileishmanial activities of artemis...

the present study was conducted to detect prevalence and risk factors for retrovirus infection of infected cats in a cat population in iran, by evaluation of 238 client-owned cats of different ages that were tested for the presence of fiv antibodies. the cats were selected from those referring to veterinary hospital of ahvaz university, southwestern iran from december 2007 to june 2010. classif...

objective: irinotecan is a botanical derivative and an anti-cancer drug with cytotoxic and genotoxic effects. the present study evaluated the effect of lactobacillus plantarum a7 on the genotoxic activity of irinotecan in a hepatocellular carcinoma cell line (hepg2) by comet assay. materials and methods: hepg2 were incubated with irinotecan (100 µm), heat-killed cells (0.025 µg/ml) + irinotecan...

objective: ferula szowitsiana has been widely used for medicinal purposes around the world. the anti-oxidant effect of f.szowitsiana had been proved. the current study aims to determine the protective effects of galbanic acid, a sesquiterpene coumarin from f. szowitsiana, against hydrogen peroxide (h2o2) - induced oxidative dna damage in human lymphocytes. materials and methods: human lymphocyt...

cystic echinococcosis is an important zoonosis in the sheep rising areas of iran. to develop a simple and reliable diagnostic method for echinococcus infection in definitive hosts, e. granulosus polyoclonal antibodies (polyabs) were prepared from adult worm in rabbit. a selected poab was used for coproantigen detection in faecal samples obtained from animals naturally infected with echinococcus...

objective: to evaluate the predictive value of some biochemical markers in the outcome of extremity vascular trauma. methods: this study comprised 30 patients with traumatic arterial injury and acute limb ischemia referred to namazi hospital affiliated with shiraz university of medical ssciences, over a period of 8 months, from sep 2009 to jul 2010. venous blood samples were drawn from distal i...

background: ˝radioadaptive response˝ is well-documented phenomenon appeared in low dose ionizing radiation received in vitro and in vivo. occupational exposure has always been a great concern for radiation workers therefore this study was performed to study radioadaptive response in terms of residual dna double strand breaks as an endpoint in peripheral blood leukocytes of occupationally expose...

ilex spinigera (aquifoliaceae) plant is an evergreen tree or shrub with thick glossy dark green leaves and red fruits. this plant has medicinal properties and has been used traditionally in northern iran for malaria treatment. the aim of this work is to evaluate the antioxidative activities and the inhibitory effect of i.spinigera on the oxidation of dna. we have found no reports about the popu...

an agar well diffusion bioassay method for determination of clarithromycin in human plasma, using micrococcus luteus atcc 9341 as the assay organism, was compared with a selective high-performance liquid chromatographic (hplc) method with uv detection. spiked plasma was used to prepare standard and control samples for both methods. the results of the bioassay analyses with spiked plasma samples...