Aim: De Ritis ratio (aspartate transaminase/alanine transaminase) may be a useful prognostic biomarker for certain malignant tumors. However, the predictive value of before treatment in preoperative staging patients with breast cancer is unknown. This study aimed to evaluate benign and diseases investigate it cancer. 
 Methods: Retrospective analysis was made clinicopathological data 301 d...

The release of lactic dehydrogenase, creatine phosphokinase, and aspartate aminotransferase from initially viable, metabolically competent adult rat heart myocytes has been examined. Freshly isolated cells contain levels of total lactic dehydrogenase, creatine phosphokinase, and aspartate aminotransferase, as well as lactic dehydrogenase and creatine phosphokinase isoenzyme profiles that are qu...

Identification of residues responsible for functional specificity in enzymes is a challenging and important problem in protein chemistry. Active-site residues are generally easy to identify, but residues outside the active site are also important to catalysis and their identities and roles are more difficult to determine. We report a method based on analysis of multiple sequence alignments, emb...

(EC 2.6.1.5,1 L-tyrosrne : 2-oxoglutarate aminotransferase), alanine aminotransferase (EC 2.6.1.2, L-alaflme :2-oxoglutarate aminotransferase), and aspartate aminotrans ferase (EC 2.6.1.1, L-aspartate : 2-oxoglutarate aminotransferase) in tumor-bearing rats. From the results and studies on various analogous conditions, the metabolism of tumor-bearing animals is discussed. It was found that the ...

Tetracarpidium conophorum leaves are used in traditional medicine for the treatment of male infertility, without considering its toxicity and side effects. In this study, we investigated the effects of T conophorum leaves on some biochemical parameters such as alanine aminotransferase, aspartate aminotransferase, bilirubin, albumin, creatinine, and uric acid. Histology of the liver and kidney w...

We appreciated the article by Gonnert and colleagues on hyperbilirubinemia from septic hepatocellular excretory dysfunction [1], a still improperly characterized issue in clinical settings. We address postoperative liver resection patients with prominently conjugated (~50 to 70 % conjugated) hyperbilirubinemia. Less relevant causes include transient insufficiency of remnant liver and prolonged ...

OBJECTIVE This study sought to determine the serum aminotransferase levels of patients with predialysis chronic kidney disease and establish their relationships with serum creatinine levels and glomerular filtration rate. METHODS Patients with chronic kidney disease were evaluated between September 2011 and May 2012. Aminotransferase and creatinine serum levels were measured using an automate...

Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet. Biochemical and hematological parameters investigated included serum protein, total cholesterol, lipid peroxidation, haemoglobin, white blood cells, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione...

Increased aminotransferases often indicate hepatic injury but are also increased with damage to heart and muscle (1 ). Testing for creatine kinase is helpful, especially when the ratio of aspartate aminotransferase to alanine aminotransferase is 3:1, a value uncommon with liver injury. In acute liver injury the aspartate aminotransferase/alanine aminotransferase ratio is usually 2:1. When measu...