BACKGROUND Evidence exists that beverages do not trigger appropriate anticipatory physiologic responses, such as cephalic phase insulin release. Therefore, it is of interest to elucidate the food properties necessary for triggering adaptive responses. Previously, we found a prolonged dose-dependent decrease in the hypothalamic functional magnetic resonance imaging signal after ingestion of a gl...

The heterodimer of Tas1R2 and Tas1R3 is a broadly acting sweet taste receptor, which mediates mammalian sweet taste toward natural and artificial sweeteners and sweet-tasting proteins. Perception of sweet taste is a species-selective physiological process. For instance, artificial sweeteners aspartame and neotame taste sweet to humans, apes, and Old World monkeys but not to New World monkeys an...

Artificial sweeteners (ASs), as a new emerging pollutant, the fate from wastewater treatment plants (WWTPs) to sea is growing concerned. In this study, distribution and polluted loading of six typical ASs were analyzed based on measurement in influent, primary effluent, secondary tertiary suspended particulate matter (SPM), sludge four WWTPs receiving waters near coast Shenzhen city, China. Ele...

Genetically mediated taste responsiveness to 6-n-propylthiouracil (PROP) has been linked to reduced acceptance of some bitter foods. In this community-based study male (n = 364) and female (n = 378) adults enrolled in a self-help dietary intervention trial were screened for PROP taster status. Respondents, aged 18--70 years, were mailed filter papers impregnated with PROP or with aspartame solu...

Carbonated and noncarbonated, sweetened blueberry flavored milks were evaluated by a trained panel. The effect of carbonation and sweetener type (sucrose, high fructose corn syrup, aspartame, and pear concentrate) on flavor properties was measured. Carbonation enhanced the sensory rating of overall flavor intensity, sweetness, and blueberry flavor. Sweetener type had a significant effect on the...