BACKGROUND AND PURPOSE Spasticity is a frequently observed motor impairment that develops after stroke; it can cause pain and disability in those affected. The objective of the present study was to evaluate the safety and efficacy of tizanidine, a centrally acting alpha(2)-adrenergic agonist, in the treatment of stroke-related spasticity. METHODS Forty-seven patients, who were a minimum of 6 ...

Association between the site of brain injury and poststroke spasticity is poorly understood. The present study investigated whether lesion analysis could document brain regions associated with the development of severe upper limb poststroke spasticity. A retrospective analysis was conducted on 39 chronic stroke patients. Spasticity was assessed at the affected upper limb with the modified Ashwo...

OBJECTIVE To investigate the long-term efficacy of neuromuscular electrical stimulation in enhancing motor recovery in the upper extremities of stroke patients. METHODS A total of 46 patients with stroke were assigned to a neuromuscular electrical stimulation group or a control group. All patients received a standard rehabilitation programme. Patients in the neuromuscular electrical stimulati...

OBJECTIVE To investigate the effects of tetanic faradic stimulation in an antagonist muscle (tibialis anterior) on agonist muscles (gastro-soleus). In addition, to show the effects of maintaining agonist muscle strength on antagonist spastic muscle group to improve gait parameters in children with spastic hemiplegia. METHODS We carried out the study at Pamukkale University, School of Physical...

OBJECTIVE The primary goal was to identify the neuroradiological and neurophysiological risk factors for upper-extremity hypertonia in patients with severe ischaemic supratentorial stroke. DESIGN Inception cohort. PATIENTS Forty-three consecutive patients with an acute ischaemic supratentorial stroke and an initial upper-extremity paralysis admitted to an academic hospital recruited over a ...

Objective: The study assessed the effect of a single session of repetitive peripheral magnetic stimulation (rpMS) combined with manual stretch on wrist and finger flexor muscle spasticity. Methods: Forty chronic patients after CNS lesion with a severe wrist and finger flexor spasticity with a Modified Ashworth Score (MAS, 0-5) of either 2, 3 or 4 participated and formed two groups. A single ses...