the effects of thiamine, ascorbic acid ami their combination an workers who are continuously exposal to lead has been investigated. in this study 60 persons in a battery industry was selected and divided into four equal groups. group i received placebo, group ii thiamine (300 mg), group iii ascorbic acid (250 mg) anil group iv thiamine (300 mg) plus ascorbic acid (250 mg) three times a day (ora...

after maxillary expansion, a long period of retention is necessary to prevent early relapse. therefore, it is beneficial to accelerate bone formation in the expanding midpalatal suture to reduce relapse. this study was designed to evaluate the effect of dietary vitamin c on osteogenesis of rat midpalatal suture during expansion.fifty-four male wistar rats were randomly divided into three groups...

An HPTLC method was developed for Qualitative and Quantitative Estimation of Gallic Acid and Ascorbic Acid in Polyherbal Tablets (Amalant and Sookshma Triphala Tablet) containing Embelica Officinalis, using precoated HPTLC silica gel 60 F254 as Stationary Phase and Mobile Phase for Gallic Acid is Toluene: Ethyl Acetate: Formic Acid (6:3:1v/v/v) and for Ascorbic Acid is Ethyl Acetate: Acetic Aci...

Background & Aims: Stroke is the third leading cause of death. Oxidative stress has a principal role in the complications of stroke. Due to this fact and the antioxidant effects of ascorbic acid, this study was designed to evaluate the effect of ascorbic acid on reduction of stroke complications in a permanent model of middle cerebral artery (MCA) occlusion in male rats. Methods: In this experi...

Efficiency was examined of microencapsulating L-ascorbic acid by polyglycerol monostearate (PGMS), and changes in the chemical and sensorial aspects of L-ascorbic acid and/or iron-fortified milk during storage were evaluated. The selected core materials were ferric ammonium sulfate and L-ascorbic acid. The highest efficiency (94.2%) of microencapsulation was found with the ratio of 5:1 as the c...

BACKGROUND Extended exposure to low levels of lead causes high blood pressure in human and laboratory animals. The mechanism is not completely recognized, but it is relatively implicated with generation of free radicals, oxidant agents such as ROS, and decrease of available nitric oxide (NO). In this study, we have demonstrated the effect of ascorbic acid as an antioxidant on nitric oxide metab...

1) The effect of 1 g daily doses of L-ascorbic acid in reducing the incidence of the common cold in a group of volunteers was compared with a control group receiving a placebo, The survey lasted 16 weeks during the winter months of 1971/1972. The results (1) showed that the 47 volunteers receiving L-ascorbic acid suffered a total of 44 colds, whereas the 43 people taking dummy pills had 80 cold...

Ascorbic acid is one of the important water soluble vitamins. It is essential for collagen, carnitine and neurotransmitters biosynthesis. Most plants and animals synthesize ascorbic acid for their own requirement. However, apes and humans can not synthesize ascorbic acid due to lack of an enzyme gulonolactone oxidase. Hence, ascorbic acid has to be supplemented mainly through fruits, vegetables...

BACKGROUND Glutathione S-transferases (GSTs) are detoxifying enzymes that contribute to the glutathione-ascorbic acid (vitamin C) antioxidant cycle. OBJECTIVE The objective was to determine whether GST genotypes modify the association between dietary vitamin C and serum ascorbic acid. DESIGN Nonsmoking men and women (n = 905) between 20 and 29 y of age were participants in the Toronto Nutri...