This study presents a designing process for refurbishing of a 32 MW rotor-generator damaged coupling. The reason of rotor damage was being hit by the quivers of an explosion. The original coupling was union with the rotor formed after a machining process on a mono block forged rotor. In some areas imposed damages caused the breaking off and detachment of some parts in the coupling flange. Becau...

Beat-to-beat variations in heart period provide information on cardiovascular control and are closely linked to variations in arterial pressure and respiration. Joint symbolic analysis of heart period, systolic arterial pressure and respiration allows for a simple description of their shared short-term dynamics that are governed by cardiac baroreflex control and cardiorespiratory coupling. In t...

Background Delayed Gandolinium Myocardium Enhancement (DE) extent on Cardiac Magnetic Resonance (CMR) is significantly correlated to biomarkers of myocardial injury in patients with acute viral myocarditis, and is a significant independent predictor of adverse cardiovascular outcome. Arterial Venrticular Coupling (VAC) is related to the efficiency of mechanical energy transfer from the heart to...

We study a nonlinear fluid-structure interaction (FSI) problem between an incompressible, viscous fluid and a composite elastic structure consisting of two layers: a thin layer (membrane) in direct contact with the fluid, and a thick layer (3D linearly elastic structure) sitting on top of the thin layer. The coupling between the fluid and structure, and the coupling between the two structures i...

Ca2+ release through ryanodine receptors (RyRs) in the sarcoplasmic reticulum is a key element of excitation-contraction coupling in muscle. In arterial smooth muscle, Ca2+ release through RyRs activates Ca2+-sensitive K+ (KCa) channels to oppose vasoconstriction. Local Ca2+ transients ("Ca2+ sparks"), apparently caused by opening of clustered RyRs, have been observed in smooth and striated mus...

BACKGROUND Heart rate turbulence (HRT) is a promising noninvasive risk stratifier for mortality after myocardial infarction. On the basis of a study of ventricular premature complex coupling interval and sympathetic nerve burst amplitude, we hypothesized that measures of HRT would increase with increased prematurity of the coupling interval. METHODS AND RESULTS Twenty-eight patients undergoin...

In this work a numerical strategy to address the solution of the blood flow in one-dimensional arterial networks through a topology-based decomposition is presented. Such decomposition results in the local analysis of the blood flow in simple arterial segments. Hence, iterative methods are used to perform the strong coupling among the segments, which communicate through non-overlapping interfac...

Ca release through ryanodine receptors (RyRs) in the sarcoplasmic reticulum is a key element of excitation-contraction coupling in muscle. In arterial smooth muscle, Ca release through RyRs activates Ca-sensitive K (KCa) channels to oppose vasoconstriction. Local Ca 21 transients (“Ca sparks”), apparently caused by opening of clustered RyRs, have been observed in smooth and striated muscle. We ...