Although phase-transfer-catalyzed asymmetric S(N)Ar reactions provide unique contribution to the catalytic asymmetric α-arylations of carbonyl compounds to produce biologically active α-aryl carbonyl compounds, the electrophiles were limited to arenes bearing strong electron-withdrawing groups, such as a nitro group. To overcome this limitation, we examined the asymmetric S(N)Ar reactions of α-...

A new series of 2-(5-nitro-2-heteroaryl)-1,3,4-thiadiazole derivatives, including nitro furan, nitro thiophene and nitro imidazole, were synthesized and screened in vitro for their inhibitory activity against eight bacterial strains. The results showed that most of the synthesized compounds were active against Gram-positive bacteria, determined by MIC method. Among them, compounds <str...

N-substituted aromatics are important priority pollutants entering the environment primarily through anthropogenic activities associated with the industrial production of dyes, explosives, pesticides, and pharmaceuticals. Anaerobic treatment of wastewaters discharged by these industries could potentially be problematical as a result of the high toxicity of N-substituted aromatics. The objective...

The vast majority of research and development activities begins with a detailed literature search to explore the current state-of-the-art. However, this becomes increasingly difficult as we go into information revolution 21st century. aim work is establish functional practical mathematical model catalyst characterization exact comparison catalysts. This outlines operation MIskolc RAnking 21 (MI...

Cocrystallization is currently having a tremendous impact on pharmaceuticals and energetic materials (energetics) and is poised to make a significant mark on other fields such as non-linear optics, ferroelectrics, and organic electronics. In the energetics field the ability of cocrystallization to combine two known explosive compounds into a novel material with distinct properties presents an e...

a series of new 2-(phenylthio) benzoylaryl hydrazones were synthesized by acid-catalyzed condensation of hydrazide 3 with corresponding aldehydes. the chemical structures of the compounds were elucidated by ft-ir, 1h-nmr and mass spectra. all newly synthesized compounds were evaluated for their antimycobacterial activities against mycobacterium tuberculosis h37rv using the microplate alamar blu...

copper (ii) phthalocyanine and 2,9,16,23 tetrakis nitro copper (ii) phthalocyaninehas been synthesized respectively from phthalonitrile and 4-nitro phthalonitrile under solvent-free condition using two different catalystsovernanodimensionalzeolites. 4-nitro phthalonitrile synthesized from phthalimide in three steps. the newly prepared compounds have been characterized by ir, uv-vis, 1hnmr and m...