PURPOSE To evaluate in a pilot study the safety and efficacy of liposomal doxorubicin, cyclophosphamide, and etoposide (LACE) when combined with antiretroviral therapy (ART) in patients with AIDS-related lymphoma (ARL). The impact of HIV viral control on therapy and survival was also assessed. PATIENTS AND METHODS Between 1994 and 2005, 40 patients at Virginia Mason Medical Center were diagno...

An industrial company requires quality control to maintain consistency from the production results so that it is able compete with other companies in world market. In sector, most processes are influenced by more than one characteristic. One tool can be used characteristic Multivariate Exponentially Weighted Moving Average (MEWMA) chart. The graph determine whether process has been controlled o...

Monitoring disturbances in process dispersion using control chart is mostly based on the assumption that quality characteristic follows normal distribution, which not case many real-life situations. This paper proposes a set of new charts homogeneously weighted moving average (HWMA) scheme, for efficient detection shifts standard deviation (σ). These are variety σ estimators and investigated as...

We have studied the influence of temperature and ARL 67156 on ATP hydrolysis in mouse and guinea pig vas deferens in order to explore the properties of the enzymatic inactivation mechanism proposed to regulate purinergic neurotransmission at the sympathetic neuromuscular junction of smooth muscle. The ectonucleotidase activity was determined by using the malachite green method to measure the in...

AIDS-related lymphomas (ARL) present high biological heterogeneity. For better characterization of this type of lymphoma, the objectives of the present study were to evaluate the expression of immunohistochemical markers of cell differentiation (CD10, Bcl-6, MUM-1) and determine cell origin profile according to Hans' classification of diffuse large B-cell lymphoma in AIDS patients. This study i...

Post-translational modification with myristoyl or prenyl groups is essential for membrane association of many small GTPases in the Ras superfamily. Two recent papers show that, rather than myristoylation, amino-terminal acetylation of the Arf-like protein Arl3p is required for Golgi targeting via an interaction with an integral membrane protein called Sys1.