Abstract Commensal gut microbiota modulates protective immune responses to viral infections at extra-intestinal sites, including the lungs. Gut dysbiosis induced by broad-spectrum antibiotic treatment appears alter adaptive immunity influenza infection (IAV/PR8). However, mechanism which microbial metabolism influences across gut-lung axis remains unclear. Here, we used flow cytometric analysis...

Streptococcus lactis metabolizes arginine by the arginine deiminase (ADI) pathway. Resting cells of S. lactis grown in the presence of galactose and arginine maintain a high intracellular ornithine pool in the absence of arginine and other exogenous energy sources. Addition of arginine results in a rapid release of ornithine concomitant with the uptake of arginine. Subsequent arginine metabolis...

conclusions in conclusion, oral l-arginine supplementation appears to improve anthropometric parameters, blood pressure values, and some blood biochemical indices associated with cardiovascular disease prevention. results significant decreases in anthropometric parameters, blood pressure (sbp, dbp), fbs, hba1c, ldl, mda (p < 0.001), tg (p = 0.02), and tc (p = 0.002) and a significant increase i...

two experiments were conducted to evaluate the effects of thyroxin in ovo injection and post hatch arginine feed supplementation on performance and cold tolerance acquisition in broilers. in experiment 1, a total of 2400 hatchings eggs were randomly assigned to four treatments: positive controls (intact or pricked with a needle), negative control (intact egg), injected with distilled water and ...

African marigold (Tagetes erecta L.) is one of the most well-known ornamental, medicinal and edible flowers in world. A factorial experiment based on completely randomized design with 20 treatments 3 replications, 60 plots 5 plants per plot were conducted order to investigate effect amino acids growth, nutritional parameters antioxidant capacity marigold. Experimental included two cultivars (‘Y...

The widely conserved twin-arginine translocases (Tat) allow the transport of fully folded cofactor-containing proteins across biological membranes. In doing so, these serve different functions ranging from energy conversion to cell division. Gram-positive soil bacterium Bacillus subtilis, Tat machinery is essential for effective growth in media lacking iron or NaCl. It was previously shown that...

We have measured the uptake of arginine into vacuolar membrane vesicles from Neurospora crassa. Arginine transport was found to be dependent on ATP hydrolysis, Mg2+, time, and vesicle protein with transported arginine remaining unmodified after entry into the vesicles. The Mg2+ concentration required for optimal arginine transport varied with the ATP concentration so that maximal transport occu...

We have shown that first-pass intestinal metabolism is necessary for approximately 50% of whole body arginine synthesis from its major precursor proline in neonatal piglets. Furthermore, the intestine is not the site of increased arginine synthesis observed during dietary arginine deficiency. Primed constant intravenous (iv) and intraportal (ip) infusions of L-[U-14C]proline, and iv infusion of...

introduction: the relation between morphine and nitric oxide release has been shown. due to important role of nitric oxide in regulation of skin blood flow, the aim of this study was to investigate the effect of nitric oxide synthase inhibitor (l-name) and nitric oxide synthesis precursor (l-arginine) on skin blood flow of intact and morphine-dependent rats. methods: skin blood flow of hind paw...