Abstract   Background: Regarding the variety of tests present for detecting and also screening   prostate cancer and also bearing in mind the advantages and disadvantages of   these tests we decided to re-evaluate these tests (total prostate specific antigen and all   of its modifications) in detecting prostate cancer in men with intermediate serum   PSAlevels.   Methods: Following a cross se...

BACKGROUND The area under the receiver operating characteristic (ROC) curve, referred to as the AUC, is an appropriate measure for describing the overall accuracy of a diagnostic test or a biomarker in early phase trials without having to choose a threshold. There are many approaches for estimating the confidence interval for the AUC. However, all are relatively complicated to implement. Furthe...

Accurate diagnosis of disease is a critical part of health care. New diagnostic and screening tests must be evaluated based on their abilities to discriminate diseased from nondiseased states. The partial area under the receiver operating characteristic (ROC) curve is a measure of diagnostic test accuracy. We present an interpretation of the partial area under the curve (AUC), which gives rise ...

When the goal is to achieve the best correct classification rate, cross entropy and mean squared error are typical cost functions used to optimize classifier performance. However, for many real-world classification problems, the ROC curve is a more meaningful performance measure. We demonstrate that minimizing cross entropy or mean squared error does not necessarily maximize the area under the ...

This paper focuses on differences in comment densities among individual programmers, and proposes to adjust the conventional code complexity metric (the cyclomatic complexity) by using the abnormality of the comment density. An empirical study with nine popular open source Java products (including 103,246 methods) shows that the proposed metric performs better than the conventional one in predi...

PURPOSE To measure tear film surface quality in healthy and dry eye subjects using three noninvasive techniques of tear film quality assessment and to establish the ability of these noninvasive techniques to predict dry eye. METHODS Thirty-four subjects participated in the study and were classified as dry eye or normal, based on standard clinical assessments. Three noninvasive techniques were...

This paper presents a novel classification framework derived from AdaBoost to classify facial expressions. The proposed framework adopts rotation-reversal invariant HOG as features. The Framework is implemented through configuring the Area under ROC curve (AUC) of the weak classifier with HOG, which is a discriminative classification framework. The proposed classification framework is evaluated...

We show that any weak ranker that can achieve an area under the ROC curve slightly better than 1/2 (which can be achieved by random guessing) can be efficiently boosted to achieve an area under the ROC curve arbitrarily close to 1. We further show that this boosting can be performed even in the presence of independent misclassification noise, given access to a noise-tolerant weak ranker.

Introduction: Emergency wards today are facing with an increasing numbers of older patients. Therefore, it seems important and essential to develop a short screening tool with an acceptable predictive power to identify the seniors being discharged from hospital and mean while are at risk of a decline in physical and mental performance, and thus, facing re-admission emergency wards in hospitals....