نتایج جستجو برای: apl
تعداد نتایج: 3971 فیلتر نتایج به سال:
These NCCN Guidelines Insights summarize several key updates to the NCCN Guidelines for Acute Myeloid Leukemia and discuss the clinical evidence that support the recommendations. The updates described in this article focus on the acute promyelocytic leukemia (APL) section, featuring recommendations for additional induction/consolidation regimens in patients with low- or intermediate-risk APL, a...
introduction: the telomeric dna together with its associated proteins protects the chromosome ends from degradation or aberrant recombination. telomerase and telomere are closely associated with development of cancers. in this study we aim to investigate the significance of telomerase activity (ta) and telomere length (tl) in patients with acute promyelocytic leukemia (apl). methods: peripher...
BACKGROUND AND PURPOSE Anticardiolipin antibodies (aCL) are associated with thrombotic phenomena including cerebral ischemia in young adults. Although aCL are directed to a neoepitope formed by phospholipid and beta2-glycoprotein I (beta2-GPI), immunoassays based on cardiolipin as target antigen are widely used. We previously demonstrated that 47% of aCL-negative systemic lupus erythematosus (S...
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis and/or pregnancy morbidity in the presence of circulating antiphospholipid antibodies (aPL). Different pathogenic mechanisms for aPL-mediated pregnancy failure have been proposed. In particular a direct effect of aPL on both maternal and fetal side of the placental tissue has been reported, since thei...
ACUTE PROMYELOCYTIC leukemia (APL) is a distinct subtype of acute myelogenous leukemia (AML), identified by the French-American-British classification as AML-M31 and cytogenetically characterized by the balanced reciprocal translocation between chromosomes 15 and 17. Patients with the common hypergranular type of APL are most often leukopenic. However, a more aggressive form of APL, characteriz...
This paper identifies major features of APL and its array oriented cousins and examines how they have influenced modern day computing facilities. You can find various aspects of APL available (sometimes acknowledged and sometimes not) in many offerings showing that APL has had a profound influence on computing. This is especially true if you include in the picture some of the early APL applicat...
introduction: arsenic has been used as an effective medicine in the treatment of severe promyelocytic leukemia in recurrence and resistance cases toward atra. in this study, it has been used as induction and maintenance therapy after remission. method & material: we studied 31 patients diagnosed by apl. a rsenic was started at a dose of 0.15 mg/kg (daily) until patient’s bone marrow remission.(...
n overview of hydrocode analysis at the Applied Physics Laboratory is presented. Starting with an Independent Research and Development project that simulated a high-velocity impact test of a full missile, the Laboratory developed a damage-scoring method for hydrocode simulations of missile impacts that opened the possibilities for a number of other applications. Applications of hydrocode analys...
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