نتایج جستجو برای: antipsychotics

تعداد نتایج: 6344  

Journal: :Journal of clinical psychopharmacology 2008
Jelle Vehof Maarten J Postma Richard Bruggeman Lolkje T W De Jong-Van Den Berg Paul B Van Den Berg Ronald P Stolk Huibert Burger

BACKGROUND Risperidone long-acting injectable (RLAI), the first second-generation depot antipsychotic, has extensively been studied before introduction. Thereafter, questions about the type of patients actually treated with RLAI in daily practice remain to be answered for making valid antipsychotic treatment comparisons involving RLAI in observational studies. OBJECTIVE We aimed to determine ...

Journal: :Revista brasileira de psiquiatria 2006
Carmen Lúcia Leitão-Azevedo Lísia Rejane Guimarães Martha Guerra Belmonte de Abreu Clarissa Severino Gama Maria Inês Lobato Paulo Silva Belmonte-de-Abreu

OBJECTIVE First and second generation antipsychotics are associated with metabolic disturbances. A cross-sectional study was designed to follow outpatients at the Schizophrenia and Dementia Program at a major teaching hospital in Porto Alegre, Brazil (Hospital de Clínicas de Porto Alegre) in order to verify whether second generation antipsychotics were associated with higher glucose and lipid l...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Bernard Masri Ali Salahpour Michael Didriksen Valentina Ghisi Jean-Martin Beaulieu Raul R Gainetdinov Marc G Caron

Since the unexpected discovery of the antipsychotic activity of chlorpromazine, a variety of therapeutic agents have been developed for the treatment of schizophrenia. Despite differences in their activities at various neurotransmitter systems, all clinically effective antipsychotics share the ability to interact with D2 class dopamine receptors (D2R). D2R mediate their physiological effects vi...

Journal: :Collegium antropologicum 2009
Dunja Degmecić Ivan Pozgain Pavo Filaković Katarina Dodig-Curković Mate Mihanović

Schizophrenia is a clinical syndrome of variable, but profoundly disruptive, psychopathology that involves cognition, emotion, perception and other aspects of behavior The Remission in Schizophrenia Working Group (RSWG) has defined criteria for symptomatic remission based on achieving and maintaining a consistently low symptom threshold for at least six consecutive months. Aim of our study was ...

Journal: :Medicinski pregled 2012
Milana Poznić Jesić Aleksandar Jesić Jasmina Babović Filipović Olga Zivanović

INTRODUCTION Extrapyramidal syndromes are significant side effects of antipsychotic therapy due to their severity, frequent occurrence and complications. This paper gives a brief summary of the literature with the emphasis on epidemiology, etiology, diagnosis and differential diagnosis, as well as the treatment of extrapyramidal disorders induced by antipsychotics. DYSTONIA Sustained muscle c...

Journal: :The British journal of psychiatry : the journal of mental science 2010
Lars Vedel Kessing Anders Frøkjær Thomsen Ulla Brasch Mogensen Per Kragh Andersen

BACKGROUND Treatment with antipsychotics seems to increase the risk of developing diabetes but the association is poorly characterised in clinical practice. AIMS To investigate and characterise the incidence of diabetes for people treated with antipsychotic medication in clinical practice. METHOD The study used the linkage of registers of all prescribed antipsychotics, antidiabetics and dia...

Journal: :Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2008
Bart Heeg Erik Buskens Marc Botteman Sue Caleo Mike Ingham Joep Damen Frank de Charro Ben van Hout

BACKGROUND In 2002, the National Institute for Health and Clinical Excellence (NICE), recommended atypical antipsychotics over conventional ones for first-line schizophrenia treatment, based on their lower risk of extrapyramidal symptoms. OBJECTIVE To estimate the incremental cost-effectiveness of atypical relative to conventional antipsychotics for the treatment of schizophrenia in the UK. ...

2017
Chunxia Ban Qunying Zhang Jie Feng Huijuan Li Qi Qiu Yuan Tian Xia Li

BACKGROUND Schizophrenia is a serious mental disorder largely manageable with atypical antipsychotics; however, these drugs have been associated with glucose/lipid metabolism issues such as diabetes and hyperlipidaemia. Apolipoprotein E (APOE) is the most abundant apolipoprotein, and APOE genotypes have been correlated with lipid metabolism phenotypes in an age-dependent manner. Studies exami...

Journal: :Psychiatria Danubina 2016
Marina Polić-Vižintin Ingrid Tripković Danijela Štimac Zvonimir Šostar Mirjana Orban

BACKGROUND The aim was to determine distribution and trends in the outpatient utilization of antipsychotics to evaluate the rationality of antipsychotic drug prescribing during the ten year period. SUBJECTS AND METHODS The epidemiological method of descriptive and analytical observation was used. Data on drug utilization from Zagreb Municipal Pharmacy were used to calculate the number of defi...

2014
Anders Prior Thomas Munk Laursen Karen Kjær Larsen Søren Paaske Johnsen Jakob Christensen Grethe Andersen Mogens Vestergaard

BACKGROUND AND PURPOSE It has been suggested that antipsychotic medication may be neuroprotective and may reduce post-stroke mortality, but studies are few and ambiguous. We aimed to investigate the post-stroke effects of preadmission antipsychotic use. METHODS We conducted a nationwide, population-based cohort study of 81,143 persons admitted with stroke in Denmark from 2003-2010. Using Dani...

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