Oxidant/antioxidant imbalance can occur in obstructive airways disease as a result of ongoing inflammation. Glutathione (GSH) plays a major role in pulmonary antioxidant protection. As an alternative or complement to anti-inflammatory therapy, augmenting antioxidant protection could diminish the effects of inflammation. We describe a case of a patient who had obstructive lung disease responsive...

Radon therapy using radon gas is performed in several countries. The main indications of this therapy are for pain-related diseases. Although several clinical studies have been reported, the mechanism underlying radon’s beneficial effects is still unknown. We have demonstrated that low-dose Xor γ-irradiation activates antioxidant functions and inhibits several kinds of oxidative damage in mice....

OBJECTIVE Ovarian senescence affects many tissues and produces a variety of symptoms and signs. We hypothesized that estrogens may also influence circulating redox balance by regulating activity of the cellular antioxidative enzyme system. We aimed to explore the impact of surgical estrogen deprivation and replacement (ERT) on the glutathione balance and antioxidant enzymes expression in fertil...

s: Introduction: Diabetes Mellitus is a heterogeneous group of disorders characterized by variable degrees of insulin resistance, impaired insulin secretion and increased glucose production. Free radical injury is important contributing factor for the development of Insulin resistance and impaired insulin secretion. Recently it has been suggested that glycation of antioxidant enzymes could alte...

Inhalation of high concentration of oxygen produces oxidative stress in men and experimental animals. Our previous experiments showed that the cough reflex is suppressed in guinea pigs after exposure to 100% O(2) for 60 hours. The aim of this study was to determine the effects of dietary antioxidant supplementation with vitamins C and E on hyperoxia-induced oxidative stress in airway and lung t...

The health-related effects of interactions between reactive oxygen species (ROS) and dietary antioxidants and the consequences of dietary antioxidant supplementation on human health are by no means clear. Although ROS, normal byproducts of aerobic metabolism, are essential for various defense mechanisms in most cells, they can also cause oxidative damage to DNA, proteins, and lipids, resulting ...

Background. The relationship and behavior of serum imunoglobulin E (IgE) level, peripheral blood mononuclear cell (PBMC) human leukocyte antigen DR (HLA-DR) expression and erythrocyte glutathione antioxidant pathway in asthma patients treated with systemic ozone therapy, have not been studied before. Methods. Asthma patients were treated about 1 year with three cycles (5 or 6 months each other)...

In the present study, in vitro antioxidant, free radical scavenging capacity, and hepatoprotective activity of methanol extracts from Polyalthia longifolia and Cassia spectabilis were evaluated using established in vitro models such as ferric-reducing antioxidant power (FRAP), 2,2-diphenyl-1-picryl-hydrazyl (DPPH(•)), hydroxyl radical (OH(•)), nitric oxide radical (NO(•)) scavenging, metal chel...

Schistosoma mansoni (S. mansoni) eggs trapped in the host liver elicit a chain of oxidative processes that may be, at least in part, responsible for the pathology and progression of fibrosis associated with schistosomal hepatitis. This study was designed to assess the protective effect of the antioxidant coenzyme-Q10 (Co-Q10) against experimental S. mansoni-induced oxidative stress in the liver...

lemon verbena (lippia citriodora) belongs tothe verbenaceae (shahpasand) family.l.citriodora is chemical  composition of the leaves plant have antimicrobial properties, refrigerant,anti-headaches one-sided, anti- pains nerve and housing, carminative, helping to digestion, relaxation, dizziness, colds therapy,  memory booster and etc.  in this study, phenolic compounds of l.citriodoraleaves were...