the present study was designed to investigate the protective effect of ethanol extracts from lindera coreana leaves (lce) on uvb-induced oxidative stress in hacat keratinocytes. the hacat cells were pretreated with lce for 24 h and then exposed to uvb (20 mj/cm2) for 2 h. uvb significantly decreased the cell viability (p<0.05). lce did not exhibit significantly cytotoxic effects and increased t...

Keywords: Background: Uremic anaemia has been the subject of several studies, since it causes serious problems. Decreased RBC production and survival seem to be due to erythropoietin deficiency combined with cell damage. Aims and Objectives: During haemodialysis, complement and leukocyte activation by contact with artificial surfaces promotes the formation of free radicals. However, the cell me...

Plant-based diet supplements help the prevention and therapy of several kinds of cancer because they contain micronutrients, which exhibit chemopreventive and chemotherapeutic activities. In present study invitro cytotoxic effect of wheat grass was evaluated on Caco2 cell line by MTT assay. Further antitumor and antioxidant activity of wheatgrass was evaluated against the Caco2 cell line induce...

BACKGROUND Launaea procumbens is used in the treatment of oxidative stress and mental disorders. The effects of Launaea procumbens methanolic extracts (LPMEs), i.e., 100 and 200 LPME mg/kg body weight (b.w.), on cognitive performance as well as on the activity of acetylcholinesterase, and antioxidant enzymes in rat brain tissue homogenates were evaluated. METHODS Thirty male Sprague-Dawley ra...

Phenolic compounds are found in seaweed species together with other substances presenting antioxidant activity. The objective of this work was to evaluate the antioxidant activity of the free phenolic acids (FPA) fraction from the seaweed Halimeda monile, and its activity to protect the expression of hepatic enzymes in rats, under experimental CCl4 injury. The antioxidant activity was measured ...

Oxidative stress and the overproduction of reactive oxygen species (ROS) play an important role in the pathogenesis of osteoarthritis (OA). Accumulating evidence has demonstrated the involvement of microRNAs (miRNAs) dysregulation in disease development and progression. In this study, we evaluated the effect of oxidative stress on miR-146a and miR-34a expression levels in human OA chondrocytes ...

This study investigated seasonal changes in the metabolic performance of spermatozoa and activity of the antioxidant enzymes in the seminal plasma of three wild boar/domestic pigs (aged 1.5 to 2.5 years) and the activity of the antioxidant enzymes in fluids of the cauda epididymidis and vesicular glands from 16 wild boar/domestic pig hybrids (aged 1 to 3 years). Parameters of the sperm metaboli...

BACKGROUND Tocotrienol (Tocomin) are naturally occurring analogues of vitamin E family and has been reported to possess a potent free radical scavenging activity. In the present study we have initially investigated protective role of tocotrienol against infection and inflammation induced alterations in tissues antioxidant defense system, as well as speculated, via in silico docking studies, tha...

BACKGROUND The effects of curcumin on the activities and gene expression of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione-S-transferase (G-ST), B-cell CLL/lymphoma 2 (Bcl-2) and insulin like growth factor-1 (IGF-1) in diabetic rats were studied. METHODS Twenty four rats were assigned to three groups (8 rats for each). Rats of first ...

background: the effects of estrogene on central nervous system are still controversial. objective: we aimed to investigate the effects of raloxifene on the antioxidant enzyme [superoxide dismutase (sod) and catalase (cat)] activities and malondialdehyde (mda) levels in brain homogenates of ovariectomized female rats and its effect on cognitive process of learning. materials and methods: female ...