This study aimed to understand the differences in disease duration, serological parameters, extra Articular Manifestation and treatment of Indian RA patients depending upon antinuclear antibody (ANA) positivity. was planned as a cross-sectional observational study, wherein 184 18 years above diagnosed tested for Antinuclear Antibody, who reported consultation at rheumatology department Medanta ...

OBJECTIVES To assess possible associations between the presence of antinuclear antibodies (ANAs) and pregnancy outcome in order to determine the significance of this test in obstetric practice. METHODS A case-control study was performed on 408 patients admitted to an obstetric high care unit and on whom ANA testing was consecutively performed. The study group consisted of 46 patients who test...

Ultraviolet (UV) irradiation or exposure to sunlight are well known but poorly understood predisposing factors of systemic lupus erythematosus (SLE) (Dubois, 1966; Freeman, Knox, and Owens, 1969). It appears from the published literature, that little attention has been paid to what actually occurs when apparently healthy individuals are exposed to UV irradiation. On a molecular level, UV irradi...

Rural inhabitants are exposed to considerable amounts of pesticides from water, soil and air. There are indications that exposure to pesticides may trigger production of antinuclear antibodies (ANA). Therefore, the question arises about the prevalence of ANA in this group. In 90 eastern-Polish rural inhabitants (RI) and 50 urban blood donors (BD), the presence of ANA in serum was tested using E...

Rowells syndrome is a rare disease, combining Lupus Erythematosus (LE) and Erythema Multiforme (EM) like lesions with characteristic immunological pattern, including speckled pattern of Antinuclear Antibodies (ANA), positive anti Ro SSA or La SSB antibodies Rheumatoid Factor (RF)