نتایج جستجو برای: antifungals
تعداد نتایج: 1520 فیلتر نتایج به سال:
OBJECTIVES The efficacy of intravenous injections of a liposomal formulation of amphotericin B (AmBisome) and amphotericin B deoxycholate (Fungizone) was evaluated in immunocompetent and temporarily leucopenic mouse models of disseminated aspergillosis using seven isolates of Aspergillus. METHODS Mice were infected with the organisms via tail veins. At 4 h after infection, antifungals were ad...
The Antifungal Susceptibility Testing method of the European Committee on Antimicrobial (EUCAST-AFST) is a reference technique for determination Minimum Inhibitory Concentration (MIC) antifungals Aspergillus fumigatus. However, it time-consuming and requires expertise. Micronaut-AM (M-AM) fast, simple, time-saving, ready-to-use new colorimetric using an indicator (resazurin) to facilitate visua...
Azadirachta indica has several medicinal uses, especially its leaves. Over 4000 years ago, Ayurvedic medicine used it for therapeutic benefits. This study examined the biological activity of Neem crude extracts and green-chemically produced Ag-NPs. TPCs TFCs were measured polyphenolic burden in consecutive extracts. DPPH, ABTS, FRAP experiments antioxidant antimicrobial against seven strains fo...
Fungal diseases are currently a serious public health problem, due to the limited number of really effective principles, and the emergence of resistant strains to the polyenic antifungals. The aim of this study was to screen, for non-polyenic antifungals production by Actinobacteria, and to validate the screening program by characterizing the produced compounds. Actinobacteria isolates were tes...
Target-specific hypersusceptible strains of Saccharomyces cerevisiae were used to screen antifungal compounds. Two novel Erg7p inhibitors were identified, providing proof of principle of the approach taken. However, observed hypersensitivities to antifungals acting via other targets imply that use of this tool to identify the mode of action requires significant deconvolution.
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