نتایج جستجو برای: antifibrinolytics
تعداد نتایج: 137 فیلتر نتایج به سال:
OBJECTIVE The objectives of this consensus conference were to evaluate the evidence for the efficacy and safety of perioperative drugs, technologies, and techniques in reducing allogeneic blood transfusion for adults undergoing cardiac surgery and to develop evidence-based recommendations for comprehensive perioperative blood management in cardiac surgery, with emphasis on minimally invasive ca...
Introduction Acquired haemophilia A (AHA) is a rare but clinically relevant bleeding disorder due to autoantibodies (inhibitors) against coagulation factor VIII (FVIII)1-3. AHA is usually triggered by infections, malignancies, autoimmune diseases, or pregnancy. Some cases associated with drug intake have also been described, but about half of cases remain unexplained and are classified as "idio...
Point-of-care testing (POCT) of coagulation parameters can help optimize transfusion practice in cardiac surgery. Antifibrinolytic agents may interfere with the laboratory and/or POCT coagulation assays. This randomized controlled study compared coagulation parameters obtained from a whole blood POCT coagulation device with a typical laboratory instrument in cardiac surgery patients receiving a...
OBJECTIVES The aim of this guideline is to provide clinicians with an understanding of the pathophysiology, prevalence, and clinical significance of myomata and the best evidence available on treatment modalities. OPTIONS The areas of clinical practice considered in formulating this guideline were assessment, medical treatments, conservative treatments of myolysis, selective uterine artery oc...
International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
Background: We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angioedema: a current state-of-the-art review: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Objecti...
Although most physicians are comfortable managing the limited anticoagulant effect of aspirin, recent administration potent P2Y12 receptor inhibitors in patients undergoing cardiac surgery remains a dilemma. Guidelines recommend discontinuation 5- to- 7 days before to reduce risk postoperative hemorrhage. Such strategy might not be feasible urgent surgery, due ongoing myocardial ischemia or at ...
Management of intraoperative fluid balance and blood conservation in adult cardiac surgery Eleftheriadis S, Stamoulis K, Ieropoulos Ch, Flossos A The reduction of homologous blood transfusions remains an important goal. The actual blood loss and the positive fluid balance during cardiac operations involving CPB result in a fall in the haematocrit and represent major risk factors for blood trans...
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