Carbapenem resistance due to acquired metallo-beta-lactamases (MBLs) is considered to be more serious than other resistance mechanisms. The aim of this study was to evaluate the antibacterial activity of Zataria multiflora Boiss and Carum copticum plants on IMP-producing P.aeruginosa strains. This experimental study was carried out on hospitalized burn patients during 2011 and 2012. Antibiotics...

The microbial resistance has become a global hazard with the irrational use of antibiotics. Infection of drug-resistant bacteria seriously threatens human health. Currently, there is an urgent need for the development of novel antimicrobial agents with new mechanisms and lower levels of toxicity. In this paper, a series of (S ,Z)-4-methyl-2-(4-oxo-5-((5-substitutedphenylfuran-2-yl) methylene)-2...

ferula persica, is the well-known species of the genus ferula in iran and has two varieties: persica and latisecta. they have both been extensively used in traditional medicine for a wide range of ailments. a great number of chemical compounds including sesquiterpene coumarins and polysulfides have been isolated from this plant. fresh plant materials, crude extracts and isolated components of f...

Objective: To explore the antibacterial activity of combined use Shuanghuanglian and cefoperazone sulbactam sodium on resistant strains Pseudomonas aeruginosa. Methods: The aeruginosa which were sensitive to selected prepare different test bacterial solutions respectively; experimental liquid Cefoperazone Sulbactam Sodium prepared separately set as groups control groups; Drug Sensitivity Tests ...

a hundred and five strains of salmonella havana were studied from the patients of pediatric hospital of tehran and tabriz during 1976-86. the sources of the strains in order to their frequency were from-stool, blood, spinal, fluid, wound and urine. from the epidemiological point of view salmonella havana is serotype of most non-typhoid salmonella. all of the strains had drug resistancy and most...

Bacteria are difficult to be eliminated because of their multi-drug resistance, which brings significant threats public health. Among the antibacterial methods, mechanobactericidal surfaces provide a possible approach solving this problem. In study, generally used mechanical sterilization is developed by fabricating nanostructured coating. The functional coating simply fabricated growing zeolit...

Article history: Received: 31 Jan 2012 Accepted: 19 Apr 2012 Available online: 29 Oct 2012 ZJRMS 2013; 15(6): 43-49 Background: As relatively avirulent enteric bacteria, enterococci usually cause infections in immune-compromised patients. The antimicrobial treatment, however, is quite challenging, since enterococci are intrinsically resistant to many antibiotics. Objective of the present study...

In this study, based on our previous derivatives of naphtho[2,3-b]furan-4,9-diones were synthesized and their antimicrobial activities evaluated. The screening these naphthoquinones revealed that the fluorine-containing NQ008 compound exhibited potent broad against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA), Gram-negative bacteria, fungi. results ratio m...

The pattern of using antibiotics in community pharmacies in Portharcourt city was investigated with a view of measuring the existing practices in the consumer use of antibacterial drugs. This will serve as a guide to health policy makers to improve rational use of drugs. The parameters investigated are the pattern of sale of antibacterial drugs, pharmacist-patient communication at the point of ...