The antibacterial activity against Staphylococcus aureus of long-chain fatty alcohols was investigated, with a focus on normal alcohols. The antibacterial activity varied with the length of the aliphatic carbon chain and not with the water/octanol partition coefficient. 1-Nonanol, 1-decanol and 1-undecanol had bactericidal activity and membrane-damaging activity. 1-Dodecanol and 1-tridecanol ha...

Antibacterial activities of aqueous, acetone, ethanol and methanol extracts of fruits of Helicteres isora (Mororphali) were studied. The fruit aqueous extracts of H. isora showed prominent antibacterial activities against E. coli, Staphylococcus epidermidis, Salmonella typhimurium and Proteus vulgaris; moderate activity against Enterobacter aerogenes, Staphylococcus aureus, Salmonella typhi and...

Natural clays have been used to heal skin infections since the earliest recorded history. Recently our attention was drawn to a clinical use of French green clay (rich in Fe-smectite) for healing Buruli ulcer, a necrotizing fasciitis ('flesh-eating' infection) caused by Mycobacterium ulcerans. These clays and others like them are interesting as they may reveal an antibacterial mechanism that co...

detected in breast cancer, ovarian tumors, and colo-rectal tumors (reviewed in Zahnow, 2002). In contrast, C/EBP␤ null mice are refractory to Ras-mediated skin tumorigenesis (Zhu et al., 2002). Thus, disruption of sig-In this issue of Cell, Lamb et al. have used a combina-naling through C/EBP␤ appears to contribute to malig-tion of molecular genetics, DNA microarray, and data nant transformatio...

antibacterial activity of the aerial extracts from xanthium brasilicum prepared in methanol, diethyl ether, petroleum benzene and an equal mixture of the three solvents were studied against bacterial laboratory standards and clinical isolates using the disk diffusion method. the best antibacterial results were obtained when methanol or the solvent mixture was used. the crude extract with the hi...

BACKGROUND The aim of this study was to investigate the antimicrobial property of peptide LL-37 sequences. MATERIAL AND METHODS Humanized antibacterial peptide LL-37 and the mutant were prepared by chemical synthesis. The physicochemical properties of antibacterial peptide LL-37 were analyzed by SWISS-MODEL online prediction tool. Molecular docking between antibacterial peptide LL-37 fragments ...

Histidine-rich glycoprotein (HRGP), an abundant heparin-binding protein found in plasma and thrombocytes, exerts antibacterial effects against Gram-positive bacteria (Enterococcus faecalis and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). Fluorescence studies and electron microscopy to assess membrane permeation showed that HRGP induces lysis o...

The antibacterial effect of aqueous garlic and cinnamon extract at five different temperatures (40 C, 60 C, 80 C, 100 C, 120 C) against five multidrug resistant bacterial isolates (2 gram negative and 3 gram positive), including Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, E. Coli and Proteus mirabilis were studied by well diffusion method. The maximum antibacterial effect of ...

Plants are rich source of antibacterial agents, which could be exploited in human disease management. Aqueous extracts of leaves of 46 plants selected based on an ethnobotanical survey from Mysore region Karnataka (India) were subjected to in vitro antibacterial activity assay against 14 important human pathogenic bacteria employing cup diffusion method. Antibacterial activity of the twelve pla...

Antibacterial property for the plastic products is very important due to their wide spread usage in many areas close to human health such as a child toy or a food package. There are some methods to make polymers antibacterial such as ionizing radiation but they can be still infected by micro organisms during usage of them. The best and easy way to obtain antibacterial polymers is melt mixing of...