نتایج جستجو برای: anti tyrosinase

تعداد نتایج: 366184  

2016
Amalia Di Petrillo Ana Maria González-Paramás Benedetta Era Rosaria Medda Francesca Pintus Celestino Santos-Buelga Antonella Fais

BACKGROUND Asphodelus microcarpus belongs to the family Liliaceae that include several medicinal plants. In the traditional medicine plants of the genus Asphodelus are used to treat skin disorders such as ectodermal parasites, psoriasis, microbial infection and for lightening freckles. In order to find novel skin depigmenting agents, the present work was carry out to evaluate antioxidant activi...

2015
Kang-Hyun Leem

This study was designed to investigate the collagen metabolism and tyrosinase activity of Olibanum extracts (OE). The currently known effects of OE are to move blood, calm pain, solve oedema, and promote tissue regeneration. The effect of OE on type I procollagen production and collagenase (matrix metalloproteinase-1, henceforth referred as MMP-1) activity in human normal fibroblasts Hs68 after...

Journal: :International journal of molecular medicine 2015
Cheng Yao Cheng Long Jin Inn Gyung Oh Chi-Hyun Park Jin Ho Chung

Melia azedarach (MA) has been used in folk medicine in Asia for the treatment of several diseases. Several constituents from MA possess anti-herpetic, anti-angiogenic and anticancer properties. The aim of the present study was to investigate the effect of a 70% ethanol extract of MA on melanogenesis and the underlying mechanisms involved. A B16F10 mouse melanoma cell line was used in our experi...

2017
Soon-Hyo Kwon Hye-Ryung Choi Youn-A Kang Kyoung-Chan Park

Resveratrol exhibits not only anti-melanogenic property by inhibiting microphthalmia-associated transcription factor (MITF), but also anti-aging property by activating sirtuin-1 (SIRT1). In this study, the relationship between depigmenting effect of resveratrol and SIRT1/forkhead box O (FOXO) 3a activation and was investigated. Resveratrol suppressed melanogenesis by the downregulation of MITF ...

Journal: :iranian journal of basic medical sciences 0
azizeh asadzadeh department of biology, science and research branch, islamic azad university, tehran, iran hajar sirous department of medicinal chemistry, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran morteza pourfarzam department of medicinal chemistry, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran parichehreh yaghmaei department of biology, science and research branch, islamic azad university, tehran, iran afshin fassihi department of biochemistry, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran

objective(s): tyrosinase is a key enzyme in pigment synthesis. overproduction of melanin in parts of the skin results in hyperpigmentation diseases. this enzyme is also responsible for the enzymatic browning in fruits and vegetables. thus, its inhibitors are of great importance in the medical, cosmetic and agricultural fields. materials and methods: a series of twelve kojic acid derivatives wer...

Journal: :Molecules 2012
Chien-Chih Chiu Han-Lin Chou Pei-Fang Wu Hsin-Liang Chen Hui-Min Wang Chung-Yi Chen

Four known compounds have been isolated from the stems of Liriodendron tulipifera, and the structures of these pure constituents were determined using spectroscopic analysis. Isolated compounds were screened for free radical scavenging ability, metal chelating power assay and ferric reducing antioxidant power assay (FRAP). The anti-tyrosinase effects of L. tulipifera compounds were calculated t...

Journal: :Bioorganic & Medicinal Chemistry Letters 2021

(S, S)-1-hydroxy-1-oxo-2-c,5-t-diphenylphospholane or Fiaud’s acid is used as a novel and effective chiral organocatalyst for bis α-aminophosphonates synthesis with excellent diastereoselectivity yields within short reaction time. All synthesized revealed good to antifungal capacity, where the six compounds 4a, 4b, 4e, 4h, 4k 4l are best fungicide inhibiting growth of Fusarium oxysporum Botryti...

Journal: :Molecules 2014
Yuxin Pang Dan Wang Zuowang Fan Xiaolu Chen Fulai Yu Xuan Hu Kai Wang Lei Yuan

The main components of sambong (Blumea balsamifera) are listed in this article. The whole plant and its crude extracts, as well as its isolated constituents, display numerous biological activities, such as antitumor, hepatoprotective, superoxide radical scavenging, antioxidant, antimicrobial and anti-inflammation, anti-plasmodial, anti-tyrosinase, platelet aggregation, enhancing percutaneous pe...

2013
Aeyung Kim Nam-Hui Yim Minju Im Young Pil Jung Chun Liang Won-Kyung Cho Jin Yeul Ma

BACKGROUND Ssanghwa-tang (SHT) is a widely used medication for the treatment of fatigue, pain, inflammation, hypothermia, erectile dysfunction, cancer, and osteoporosis in Asia, however, role of SHT on the melanin synthesis has not been checked previously. Thus, the present study was designed to determine the effect of SHT on α-melanocyte stimulating hormone (α-MSH)-induced melanogensis and its...

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