نتایج جستجو برای: anti neuronal antibodies
تعداد نتایج: 586905 فیلتر نتایج به سال:
BACKGROUND Patients with neuroendocrine-related tumors and paraneoplastic encephalomyelitis (PEM) or paraneoplastic sensory neuronopathy (PSN) develop high titers of antibodies, called anti-Hu, against neuronal proteins expressed in their tumors, usually small cell lung cancer (SCLC). These tumors appear to be more indolent than those not associated with anti-Hu antibodies. The aims of this stu...
Since anti-NMDA receptor (NMDAR) encephalitis was first described almost a decade ago, the family of disorders associated with antibodies against neuronal surface antigens is one of the most rapidly expanding categories of neurologic disease. With this growth comes a paradigm shift in neurology—autoimmune encephalitis has evolved from an often vaguely defined clinical syndrome to a group of pre...
BACKGROUND: BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is the main causative agents of neonatal calf diarrhea. Passive transfer of antibodies that is derived from the dams of the calves through their colostrum plays an important role in disease prevention. OBJECTIVES: To determine the presence of natural specific antibodies against K99 antigen in dam’s serum and colostrum as well as in...
Background: Hepatitis C virus infection (HCV) is a main health problem in our country. It is thought that the transmission of hepatitis C virus (HCV) through the endoscopic procedures is a rare event. The aim of this study was to evaluate the risk of conventional disinfection in the transmission of HCV. Materials and methods: A prospective study, comprising 456 consecutive upper gastrointestin...
Anti-GM1 ganglioside autoantibodies are used as diagnostic markers for motor axonal peripheral neuropathies and are believed to be the primary mediators of such diseases. However, their ability to bind and exert pathogenic effects at neuronal membranes is highly inconsistent. Using human and mouse monoclonal anti-GM1 antibodies to probe the GM1-rich motor nerve terminal membrane in mice, we her...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons. Although the etiology of ALS is obscure, genetic studies of familiar ALS suggest a multifactorial etiology for this condition. Similarly, there probably are multiple causes for sporadic ALS. Autoimmune-mediated motor neuron dysfunction is one proposed et...
BACKGROUND Nodding syndrome (NS) is a seemingly progressive epilepsy disorder of unknown underlying cause. We investigated association of pyridoxal-phosphate serum levels and occurrence of anti-neuronal antibodies against N-methyl-D-aspartate (NMDA) receptor and voltage gated potassium channel (VGKC) complex in NS patients. METHODS Sera of a Tanzanian cohort of epilepsy and NS patients and co...
Objective: To investigate possible immunological humoral correlates in newly diagnosed adult-onset generalized tonic-clonic epilepsy among Iranian patients before and after sodium valproate treatment. Patients and Methods: 72 adult patients with newly diagnosed idiopathic generalized tonic-clonic epilepsy were recruited. Serum antinuclear antibodies (ANA), anti-cardiolipin antibodies (aCL), a...
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