Erythrocyte and plasma cholinesterase activities were measured biweekly in one group of 22 subjects for a year and daily for three weeks in another group of nine men. The average range [i.e., (range/mean) X 100] of activity of erythrocyte cholinesterase in men during a year was 8% and during three weeks was 5%. For plasma, the corresponding values were 25% and 12%. The average ranges for erythr...

Erythrocyte acetylcholinesterase and plasma cholinesterase was estimated in 50 normal pregnant women and 22 age matched normal non-pregnant women. Plasma cholinesterase was significantly decreased while erythrocyte cholinesterase was significantly increased during pregnancy. These changes may be related to altered haemodynamics and or other inter-related changes occurring in pregnancy.

The present study was designed to evaluate the neuroprotective effect of Erythropoietin (EPO) in brain of memory impaired mice. Memory impairment was produced by THP in different groups of animals. Morris water maze (MWM) and Elevated plus maze (EPM) test was employed to assess learning and memory. At the end of study brain anticholinesterase (AchE) activity was estimated. Administration of EPO...

Copper and Zinc have been found to be potent inhibitors of pseudo-cholinesterase of human plasma and true-cholinesterase of erythrocytes and rat brain.

BACKGROUND Organophosphate pesticides act as cholinesterase inhibitors. For those with agricultural exposure to these chemicals, risk of potential exposure-related health effects may be modified by genetic variability in cholinesterase metabolism. Cholinesterase activity is a useful, indirect measurement of pesticide exposure, especially in high-risk individuals such as farmworkers. To understa...

We have developed a succinyldicholine-based assay for serum cholinesterase (EC 3.1.1.8) to help establish whether patients with suspected sensitivity to drugs of this type have enzyme abnormalities that cannot be detected by conventional laboratory techniques. Although the method discriminates between cholinesterase activities of drug-sensitive and nonsensitive people as well as an assay involv...

Several properties of the cholinesterase from Phaseolus aureus Roxb. and of pectin (methyl) esterases from both Phaseolus aureus and Lycopersicon esculentum (L.) Mill. are contrasted. Cholinesterase activity is inhibited by all of the concentrations of NaCl tested, from 0.05 m to 0.9 m, a property which differs sharply from published data pertaining to pectin esterase. Although crude preparatio...

Article history: Received on: 20/05/2013 Revised on: 03/06/2013 Accepted on: 17/06/2013 Available online: 30/07/2013 Salvia essential oils isolated by hydrodistillation from the plant’s commercial dried aerial parts(Fig.1),have powerful biological activity and pharmacological properties. The oils contain more than 100 different bioactive compounds, which mainly include Monoterpene hydrocarbons,...

Background: Alzheimer's disease (AD) is the most common brain disorder and remains a major health concern worldwide. Considering highly complex mechanisms of AD, search for agents based on multitarget-directed ligands (MTDLs) strategy to treat AD may be more promising than traditional “one drug-one target” strategy. Inhibition Poly (ADP-ribose) polymerases-1 (PARP-1) has potentially therapeutic...