Quinones such as 1,4-naphthoquinones are abundant in nature and naphthoquinone based natural products are known to possess anticancer activity. This pharmacophore is known to convey anticancer activity to some drugs such as streptonigrin, mitomycin A, etc. We synthesized and characterized different classes of naphthoquinone derivatives including bis naphthoquinone, 2-arylaminonaphthoquinone, be...

Unlike cytotoxic chemotherapy, cancer immunotherapy offers targeted therapies that exploit the effector mechanisms of immune system to combat cancer. However, most therapeutic strategies have so far focused predominantly on orchestration adaptive responses anti-cancer immunotherapies. Unfortunately, emergence resistance and associated severe toxicities rendered this modality treatment imperfect...

Geraniol is an acyclic monoterpenoid compound, which exists widely in aromatic plants. has antibacterial and anti-inflammatory effects. Recently, it been found that geraniol a strong effect on improving immune function anti-tumor. Many experimental evidences support good the treatment or prevention of different types tumors, such as breast cancer, lung liver pancreatic colon prostate etc. also ...

background and aim: colon cancer is the third most prevalent cancer in iran. prolonged colon inflammation is an important factor, in the development of colon cancer. ginger has anti-inflammatory properties due to its content of [6]-gingerol and hence can play a role in the prevention of colon cancer. in this research the effects of ginger extract on reducing expression of the cox-2 gene in ht-2...

Background: Trace elements play an important role in a number of biological processes. Astaxanthin (ASX), a carotoid pigment found in certain marine plant and animals, has shown anti cancer and anti free radical properties. This work intended to understand the effect of Astaxanthin in breast cancer (invasive ductal carcinoma, IDC) by using micro-pixe method. For this aim the concentratio...

Cancer is a major cause of death worldwide, as exemplified by millions cancer diagnoses every year. The use chemotherapy in treating has many disadvantages which include recurrence cancer, associated with drug resistance, and severe side effects that are harmful to the patients. A better source anticancer drugs can come from nature. Strobilanthes crispus (S. crispus) herbal medicinal plant indi...

Abstract Cervical cancer is a typical characterized by abnormal cell growth in the cervical area. Ginkgo biloba L. deciduous tree of genus , possessing anti-cancer effects. The aim this study was to explore effect strain J1 from on apoptosis cells. Bacteriostatic activity test, MTT assay and Flow cytometry were used study. Crude extract fermentation reduced cancer. crude broth had good inhibito...