نتایج جستجو برای: anti anxiety agents

تعداد نتایج: 758574  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Stefan O Reber Philip H Siebler Nina C Donner James T Morton David G Smith Jared M Kopelman Kenneth R Lowe Kristen J Wheeler James H Fox James E Hassell Benjamin N Greenwood Charline Jansch Anja Lechner Dominic Schmidt Nicole Uschold-Schmidt Andrea M Füchsl Dominik Langgartner Frederick R Walker Matthew W Hale Gerardo Lopez Perez Will Van Treuren Antonio González Andrea L Halweg-Edwards Monika Fleshner Charles L Raison Graham A Rook Shyamal D Peddada Rob Knight Christopher A Lowry

The prevalence of inflammatory diseases is increasing in modern urban societies. Inflammation increases risk of stress-related pathology; consequently, immunoregulatory or antiinflammatory approaches may protect against negative stress-related outcomes. We show that stress disrupts the homeostatic relationship between the microbiota and the host, resulting in exaggerated inflammation. Repeated ...

Akbar Hajizadeh Moghaddam Ali Roohbakhsh, Karim Mahmoodi Delfan

Objective(s) The effect of testosterone on anxiety-like behaviors has been the subject of some studies. There is evidence that testosterone modulates anxiety via GABA (gama aminobutyric acid) and GABAergic system. The involvement of GABAC receptors in those effects of testosterone on anxiety-like behaviors of the rats was investigated in the present study. Materials and Methods A group of ra...

Journal: :Journal of palliative medicine 2007
Clare White Mary Ann McCann Neil Jackson

Terminal restlessness is a term frequently used to refer to a clinical spectrum of unsettled behaviors in the last few days of life. Because there are many similarities between the clinical pictures observed in terminal restlessness and delirium, we postulate that at times what is referred to as terminal restlessness may actually be an acute delirium sometimes caused by medication used for symp...

Journal: :Canadian journal of psychiatry. Revue canadienne de psychiatrie 1998
N Casacalenda J P Boulenger

OBJECTIVE To review the efficacy of anxiolytics (alprazolam and azapirones) in major depressive disorder (MDD) and that of antidepressants in generalized anxiety disorder (GAD), thereby exploring the possible theoretical and clinical implications of this efficacy. METHOD A Medline literature search was performed for the period January 1980 to September 1997 of randomized, double-blind compari...

Journal: :The Journal of clinical psychiatry 1999
S M Stahl

Original drug classifications from the 1960s through the 1970s and into the 1980s emphasized that there were important distinctions between the antidepressants (e.g., tricyclic antidepressants) and the anxiolytics (e.g., benzodiazepines and buspirone) available at that time. This emphasis reflected the diagnostic notions prevalent at that time, which tended to dichotomize major depressive disor...

Journal: :The international journal of neuropsychopharmacology 2002
Arif Khan Shirin Khan Walter A Brown

One measure of a treatment's effectiveness is the regularity with which it proves superior to placebo. That measure also tells us about the consequences of using a treatment as a standard against which to test a new agent. To assess the frequency with which approved and presumably effective antidepressants and anxiolytics show statistical superiority over placebo, we reviewed placebo-controlled...

2018
Justin S Feinstein Sahib S Khalsa Hung-Wen Yeh Colleen Wohlrab W Kyle Simmons Murray B Stein Martin P Paulus

Floatation-REST (Reduced Environmental Stimulation Therapy) reduces sensory input to the nervous system through the act of floating supine in a pool of water saturated with Epsom salt. The float experience is calibrated so that sensory signals from visual, auditory, olfactory, gustatory, thermal, tactile, vestibular, gravitational and proprioceptive channels are minimized, as is most movement a...

2014
REKHA MEHANI

To study anxiolytic and antidepressant effect of Astaxanthin as an adjuvant to standard drug.In this study, to investigate the effects of astaxanthin on anxiety and depression,we performed some behavioural trials including elevated plus maze test, hole-board test, forced swim test, and tail suspension test.Astaxanthin ( 3 mg/kg/day for 15 days, orally) significantly increased the time spent in ...

2012
Matthew O. Parker Mollie E. Millington Fraser J. Combe Caroline H. Brennan

Zebrafish are a widely utilised animal model in developmental genetics, and owing to recent advances in our understanding of zebrafish behaviour, their utility as a comparative model in behavioural neuroscience is beginning to be realised. One widely reported behavioural measure is the novel tank-diving assay, which has been often cited as a test of anxiety and stress reactivity. Despite its wi...

Journal: :European journal of pharmacology 2005
Allan V Kalueff Pentti Tuohimaa

Grooming is an important part of rodent behavioural repertoire, representing a complex hierarchically ordered cephalo-caudal sequence of patterns sensitive to stress and various drugs. Gamma-aminobutyric acid (GABA) is involved in the regulation of both anxiety and grooming behaviours. This study investigated the predictive validity of grooming behavioural microstructure as a marker of anxiety,...

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