Objective: To explore the efficacy of ethanolic leaf extract of Aristolochia indica L. in bacterial and worm infections using experimental models. Methods: Preliminary phytochemical screening was evaluated by following standard procedure. Antibacterial activity was carried out by disc diffusion method and anthelmintic effect of the plant extract was determined based on time taken for paralysis ...

BACKGROUND Whipworms and blood flukes combined infect almost one billion people in developing countries. Only a handful of anthelmintic drugs are currently available to treat these infections effectively; there is therefore an urgent need for new generations of anthelmintic compounds. Medicinal plants have presented as a viable source of new parasiticides. Ajania nubigena, the Bhutanese daisy, ...

Many parasitic helminthes of veterinary importance have genetic features that favor development of anthelmintic resistance, this becoming a major worldwide constrain in livestock production. The development of anthelmintic resistance poses a large threat to future production and welfare of grazing animals. Development of variable degrees of resistance among different species of gastrointestinal...

Carica papaya (pawpaw) is an economically important fruit of the tropics and subtropics. The fruit and leaves of pawpaw contain proteins and alkaloids of potential important medicinal, industrial and pharmaceutical applications; these include antimicrobial, anthelmintic and antifertility effects. These effects are attributed to many biologically active compounds of C papaya; Benzyl isothiocyana...

PURPOSE OF REVIEW With the London Declaration on neglected tropical disease (NTD), we are entering a new era of combating NTDs. However, the worldwide prospects of increased mass drug administration (MDA) treatments warrant caution on the development of anthelmintic resistance. In this review, we discuss the practical implications of MDA programs on the development of anthelmintic resistance in...