PURPOSE To determine the presence and magnitude of the photopic negative response (PhNR) component of the electroretinogram (ERG) in the mouse eye and to test if it is altered by short-term elevation of intraocular pressure (IOP). METHODS Photopic and scotopic ERGs were recorded from 12-month-old C57BL/6J mice and analyzed for photoreceptoral responses (a-wave), bipolar cell responses (b-wave...

PURPOSE To describe bilateral corneal alterations through confocal microscopy in a patient affected by Cowden syndrome (CS). METHODS Evaluation of Schirmer's, fluorescein, and lissamine green dye tests. Confocal microscopy was performed in both eyes to investigate corneal abnormalities. RESULTS Slit lamp observation showed the focal involvement of anterior stromal and epithelial layers. Sch...

Purpose. To assess the amount and the axis orientation of anterior and posterior corneal astigmatism after refractive lenticule extraction (ReLEx) for myopic astigmatism. Methods. We retrospectively examined 53 eyes of 53 consecutive patients (mean age ± standard deviation, 33.2 ± 6.5 years) undergoing ReLEx to correct myopic astigmatism (manifest cylinder = 0.5 diopters (D)). Power vector anal...

Purpose To assess corneal hydration control across a range of severity of Fuchs' endothelial corneal dystrophy (FECD) by measuring the percent recovery per hour (PRPH) of central corneal thickness after swelling the cornea and to determine its association with corneal morphologic parameters. Methods Twenty-three corneas of 23 phakic FECD patients and 8 corneas of 8 healthy control participant...

We read with interest the recent article by Alomar et al. and would like to congratulate the authors for their detailed description of confocal microscopy observations in corneas with chronic edema and their excellent description of the correlation of these observations to histopathologic findings. We certainly appreciate the vast amount of time that was spent acquiring images of such excellent...

In 25 eyes, age range 60-80 years, in purpose of preoperative treatment prior to cataract surgery, measurements of the radius of curvature as well as main meridians of the anterior and posterior corneal surfaces were performed. Average value of the curvature of the anterior corneal surface (R1) was R1 = 7.84 mm, while posterior radius (R2) was 6.4 mm. Main meridian of the anterior corneal surfa...

Objective. To report a case of toxic anterior segment syndrome (TASS) that was caused by inadvertent anterior chamber and cornea stromal injection with high dose gentamicin following cataract surgery. Methods. Case report. Results. We report a 72-year-old female patient who developed TASS that was caused by high dose gentamicin (20 mg/0.5 mL), which was inadvertently used during the formation o...

BACKGROUND The measurement of dynamic parameters, such as the length of applanation and the amplitude of deformation, is significant for evaluating corneal properties. Most of the corneal properties (related to shape) including the anterior corneal curvature and the thickness of cornea can be easily measured using some existing techniques. However, they only provide the static or pseudo-dynamic...