Growth promoters play an important role in the animal agriculture industry as they facilitate to improve productivity mainly through reduction of pathogenic bacterial load in the gut. Ban and restrictions on the usage of Antibiotic Growth Promoters (AGP) due to public health concerns has made it essential to search alternatives from the herbal sources. But at the same time it is tricky to choos...

Abstract Background Inappropriate use of antimicrobials in both humans and animals is a key driver antimicrobial resistance (AMR). In addition, human behaviours such as poor disposal the environment can increase their exposure to microbes which impact on animals. However, evidence access, for at community level Uganda limited. This study therefore explored among Wakiso district, Uganda. Methods...

INTRODUCTION Antibiotics are chemotherapeutic agents used for the clinical management of infectious diseases in humans, plants and animals. However a sizeable fraction of antibiotics produced every year all over the world is used for non-therapeutic purposes. In US alone, about 24.6 million pounds of antibiotics are used in animal agriculture annually and a substantial portion of this is used a...

We studied the effects of carbon starvation and of varying the growth rate on the activity of each of the two tandem ribosomal RNA promoters from the rrnA operon of Escherichia coli. The cellular abundance of plasmid-encoded transcripts arising at promoters P1 and P2 and terminating at the ribosomal RNA terminator in promoter-terminator fusions, together with transcript turnover rates, was used...

Bacteria use a variety of mechanisms to direct RNA polymerase to specific promoters in order to activate transcription in response to growth signals or environmental cues. Activation can be due to factors that interact at specific promoters, thereby increasing transcription directed by these promoters. We examine the range of architectures found at activator-dependent promoters and outline the ...

Antibiotic-resistant bacterial infections result in higher patient mortality rates, prolonged hospitalizations, and increased health care costs. Extensive use of antibiotics as growth promoters in the animal industry represents great pressure for evolution and selection of antibiotic-resistant bacteria on farms. Despite growing evidence showing that antibiotic use and bacterial resistance in fo...