نتایج جستجو برای: angiotensinogen m235t polymorphism

تعداد نتایج: 109322  

Journal: :Arquivos brasileiros de cardiologia 2007
Silvia Regina Sampaio Freitas Pedro Hernan Cabello Rodrigo Soares Moura-Neto Luciana Cresta Dolinsky Marcio Neves Bóia

OBJECTIVE In the present study, we evaluated the contribution of six genetic polymorphisms of the Renin-Angiotensis-Aldosterone system (RAAS) and clinical risk factors in the development of essential hypertension in a Brazilian rural population in the Amazon region. METHODS Eighty-two hypertensive patients and seventy-eight normotensive individuals were evaluated. Genotyping for renin (REN G1...

2013
S.G. Lima M.F.P.M. Albuquerque J.R.M. Oliveira C.F.J. Ayres J.E.G. Cunha D.F. Oliveira R.R. Lemos M.B.R. Souza O. Barbosa e Silva

Exaggerated blood pressure response (EBPR) during the exercise treadmill test (ETT) has been considered to be a risk factor for hypertension. The relationship of polymorphisms of the renin-angiotensin system gene with hypertension has not been established. Our objective was to evaluate whether EBPR during exercise is a clinical marker for hypertension. The study concerned a historical cohort of...

Journal: :Hypertension 1999
T Niu J Yang B Wang W Chen Z Wang N Laird E Wei Z Fang K Lindpaintner J J Rogus X Xu

The gene encoding angiotensinogen (AGT) has been widely studied as a candidate gene for hypertension. Most studies to date have relied on case-control analysis to test for an excess of AGT variants among hypertensive cases compared with normotensive controls. However, with this design, nothing guarantees that a positive finding is due to actual allelic association as opposed to an inappropriate...

Journal: :Hypertension 1999
Y Y Zhao J Zhou C S Narayanan Y Cui A Kumar

-Angiotensinogen is the glycoprotein precursor of 1 of the most potent vasoactive hormones, angiotensin II. Human angiotensinogen gene contains a C/A polymorphism at -20 located between the TATA box and transcriptional initiation site. We show here that when nucleoside A is present at -20, this sequence binds to the estrogen receptor. We also show that transcriptional activity of reporter const...

1999
Yan Yan Zhao Jie Zhou Chittampalli S. Narayanan Yanning Cui Ashok Kumar

Angiotensinogen is the glycoprotein precursor of 1 of the most potent vasoactive hormones, angiotensin II. Human angiotensinogen gene contains a C/A polymorphism at 220 located between the TATA box and transcriptional initiation site. We show here that when nucleoside A is present at 220, this sequence binds to the estrogen receptor. We also show that transcriptional activity of reporter constr...

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