PurposeWe aimed to describe the epidemiology of angioid streaks (AS) and pseudoxanthoma elasticum (PXE), which are rare diseases, using a national claims database.DesignThis was population-based longitudinal cohort study.ParticipantsA total 126 million individuals were covered by universal health coverage system in Japan.MethodsWith permission from Ministry Health, Labor Welfare (MHLW), we acce...