The eight publications in the November issue of the journal (one review and seven original articles) are all about pregnancy. To some of our readers this will be a surprise—there is a popular myth that Molecular Human Reproduction (MHR) loses interest in reproduction after implantation. The papers we publish this month demonstrate that this just is not true.We consider scientific reports on top...

Technological advances in medicine often lead to a better understanding of disease processes. Computerized neuroimaging is an advance that has had a more profound impact than most. In schizophrenia, it has shown brain changes of at least a quantitative nature to exist in a significant minority of patients. Until recently, these changes were seen as evidence for an underlying neurodegenerative p...

Respiratory and fermentative pathways coexist to support growth and product formation in Pichia stipitis. This yeast grows rapidly without ethanol production under fully aerobic conditions. and it ferments glucose or xylose under oxygen-limited conditions. but it stops growing within one generation under anaerobic conditions. Expression of Saccharomyces cerevisiae URA1 (ScURA1) in P. stipitis e...

A study of oral lichen planus on 150 extending over 30 years was undertaken, a female predominance was noted. Most patients (47.3%) were from the intermediate and non manual worker class. The buccal mucosa (89.3%) followed by the gingival (39.3%) were found to be the most commonly affected sites. Soreness featured as the most common presenting complaint (56.6%). The keratotic lesion was the mos...

The literature on alterations in brain structure and function in schizophrenia, particularly in relationship to impairments in cognitive, motor, and affective functions, has made it increasingly clear that changes in the function of a single brain region cannot explain the range of impairments seen in this illness.1–4 This realization has led to a surgence of interest in studies examining neuro...

A simple and numerically stable 2-term partial differential equation characterizing the price of any type of arithmetically averaged Asian option is given. The approach includes both continuously and discretely sampled options and it is easily extended to handle continuous or discrete dividend yields. In contrast to present methods, this approach does not require to implement jump conditions fo...

In this issue of Thrombosis and Haemostasis a collection of review articles and original contributions have been published coinciding with the “17th International Congress on Fibrinolysis and Proteolysis” to be held in Melbourne, Australia, at the end of March 2004. It is widely acknowledged that the field of fibrinolysis and proteolysis has enormously expanded since the early discoveries of, f...

Conventional electronics based on silicon, germanium, or compounds of gallium require prohibitively expensive investments. A state-of-the-art microprocessor fabrication facility can cost up to $15 billion while using environmentally hazardous processes. In that context, the discovery of solution-processable conducting (and semiconducting) polymers stirred up expectations of ubiquitous electroni...

Churchill, Dennis and Brian A. MacVicar. Biophysical and phar(Berridge and Dupont 1994; Snutch and Reiner 1992; Tsien macological characterization of voltage-dependent Ca channels et al. 1988, 1991). in neurons isolated from rat nucleus accumbens. J. Neurophysiol. Ca currents have been classified into low-threshold 79: 635–647, 1998. The nucleus accumbens (NA) has an integ(Akaike 1991; Huguenar...

Clinical and experimental research have provided anatomical, pharmacological, and behavioral evidence for a prominent prefrontal dysfunction in schizophrenia. Negative symptoms and behavioral disorganization in the disorder can be understood as a failure in the working memory functions of the prefrontal cortex by which information is updated on a momentto-moment basis or retrieved from long-ter...