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Background and Objective: Memantine is a glutamate N-Methyl-D-Aspartate (NMDA) receptor antagonist with low receptor binding affinity which is currently used in moderate to severe Alzheimer’s disease. So far, the effect of memantine on stress system has not been investigated. This study focused on the effects of both peripheral and intra-accumbal memantine administration on plasma corticosteron...
Background and purpose: The adrenergic system is known to have modulatory influence on anxiety-related behaviour both in human and animals. Dorsal hippocampus is an important brain site in modulation of neurotransmittery and neuroendocrinology of anxiety. The present study, was designed to evaluate the interactions between adrenergic and opioidergic systems in dorsal hippocampus on anxiety. Ma...
Introduction: Similarities in the memory impairment between Alzheimer patients and scopolamine treated animals have been reported. In the present study, the possible role of α-adrenergic receptors of the dorsal hippocampus on scopolamine state-dependent memory in adult male Wistar rats was evaluated. Methods: The animals were bilaterally implanted with chronic cannulae in the CA1 regions o...
background during laparoscopy, insufflation of an inert gas in the peritoneal cavity creates a working space to facilitate surgery. the space should be large enough to facilitate surgery without increasing intra-abdominal pressure (iap) over a threshold limit (usually 15 mm hg). objectives this experimental study was performed to evaluate the effects of increasing in intra-abdominal pressure on...
Despite many advances in the field of cancer treatment, intra-cranial tumor cases still have a poor prognosis. This research has been carried out in order to describe age and sex distributions and histopathological characteristics and site of intra-cranial tumors. We studied 425 patients with intra-cranial tumor whose samples were examined in pathology center of Imam Khomeini hospital from 1991...
In this work, adsorption kinetics were investigated in order to remove the acid blue 62 off the aqueous solutions using mesoporous silicate SBA-15 loaded with tannic acid (tannin-SBA-15). Nitrogen adsorption and desorption test (BET), X-ray diffraction (XRD) and Fourier transform infra-red spectroscopy (FT-IR) analysis characterize synthesized composite. The impacts of some parameters such as P...
Background & Aims: Increase in abdominal pressure can lead to the so-called intra–abdominal compartment syndrome (ACS) that is often observed during the first 24 hours after sever abdominal trauma and surgery. Measurement of the intra abdominal pressure through the bladder as a non-invasive measurement can provide a quick and accurate assessment of abdominal pressure changes. This study was per...
Uveitis is a major cause of vision loss. Methotrexate (MTX) has been widely used in uveitis due to its relatively safe profile. The purpose of this study was to evaluate the effects of two different dosages of MTX via intra-vitreal administration for treatment of endotoxin induced uveitis (EIU) in an experimental model. Thirty-five healthy rabbits were randomly divided into four groups and all ...
intra-abdominal desmoplastic small round cell tumor is a rare entity with a few reports worldwide. this tumor commonly occurs in children and adolescent and occurrence in adult age group is very rare. here, we describe an adult male with symptoms of intestinal obstruction due to abdominal mass, located in splenic flexure. after resection, the diagnosis of intra-abdominal desmoplastic small roun...
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