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The ability of pulmonary surfactant to reduce alveolar surface tension requires adequate expression of surfactant protein B (SP-B). Dexamethasone (DEX, 10(-7) M) increases human SP-B mRNA stability by a mechanism that requires a 126-nt-long segment (the 7.6S region) of the 3'-untranslated region (3'-UTR). The objective of this study was to identify sequences in the 7.6S region that mediate regu...
Sputter deposited MgO thin films with the B1 crystal structure and ~002! film texture are used as seed layers to improve the texture and magnetic properties of the CoCrPt/Cr magnetic thin films on glass substrates for longitudinal recording. The desired ~002! textured Cr underlayers are usually obtained by sputtering Cr onto heated substrates. However, it is found that the MgO seed layers can i...
Gene variants derived from Neanderthals or Denisovans can be associated with polygenic traits, validating the utility of notion about archaic gene flow. Endoplasmic reticulum aminopeptidase 1 (ERAP1) haplotypes control disease risk primarily mediated by HLA-C*06:02, HLA-B*27 and HLA-B*51 for psoriasis, ankylosing spondylitis (AS) Behçet's (BD). In this genetic interaction corresponds to differe...
Aqueous extracts of nine medicinal plants were bioassayed against larvae of Culex quinquefasciatus Say and Aedes aegypt (L.). Among these plants, the long pepper, Piper retrofractum Vahl (Piperaceae), showed the highest level of activity against mosquito larvae. To gain more information on larvicidal activity of P. retrofractum, fresh fruits of this plant were extracted in water and the extract...
PURPOSE Advanced cancer patients with disease progression develop cachexia. Nevertheless, cancer patients at nutritional risk have shown improved body weight and quality of life with oral nutritional supplements. METHOD This was a randomized controlled trial in adult female cancer patients (n = 63) attending palliative clinics, with symptoms of cachexia. Eligible patients were randomly distri...
BACKGROUND The protective effect of two isolates of an entomopathogenic fungus, Metarhizium anisopliae (DEMI 002 and Iran 437C) on the adult stage of Varroa destructor was evaluated in comparison with fluvalinate strips in the field. METHODS A total of 12 honey bee colonies were provided from an apiculture farm. The selected hives were divided into 4 groups (3 hives per group). The first grou...
Introduction BS is an autosomal dominant monogenic granulomatous disease due to gain of function mutations at or near the NACHT domain of NOD2. It is characterized by a triad of granulomatous polyarthritis, uveitis and rash. Retrospective work by our group showed a life time risk of ocular involvement of 60% with significant morbidity and poor visual outcome. Prospective studies on natural hist...
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