Anchoring microtubules to the centrosome is critical for cell geometry and polarity, yet the molecular mechanism remains unknown. Here we show that the conserved human Msd1/SSX2IP is required for microtubule anchoring. hMsd1/SSX2IP is delivered to the centrosome in a centriolar satellite-dependent manner and binds the microtubule-nucleator γ-tubulin complex. hMsd1/SSX2IP depletion leads to diso...

I discuss how the Multiple Pathway Anchoring and Adjustment model is similar to and different from the Feldman and Lynch accessibility-diagnosticity model, elaborated as an anchoring and adjustment model by Lynch, Marmorstein, andWeigold. Cohen and Reed’s concept of representational sufficiency embraces both attitude coherence and retrieval fluency; these map to prior operationalizations of dia...

Perceptual anchoring is the process of linking action to the appropriate objects in the environment via perception. The pivot of anchoring is the inclusion of micro-models of the world, or anchors, into a controller. In this paper, we propose to use anchors to focus the perceptual eeort according to the current needs of the controller. We describe an active gaze control strategy able to maintai...

We describe a new approach to representing vague or uncertain information concerning spatial location. Locational information about objects in information space is expressed through various anchoring relations which enable us to state exactly what is known regarding the spatial location of an object without forcing us to identify that location with either a precise region in the embedding space...

I model a scenario in which investors do not know the payoff distributions of relatively newer firms and use the payoff distribution of similar well-established firms as starting points. The starting distributions are then adjusted for size, volatility, and other differences. Anchoring bias (Tversky and Kahneman (1974)) implies that such adjustments typically fall short. I show that adjusting c...

Comparative genomics makes an extensive use of sequence comparison to identify genes and their possible functions. A whole genome search needs to be pruned by a heuristic (the anchoring step) to ensure a reasonable execution time. We explored anchoring schemes that could solve the classical trade-off between speed and quality: speed is obtained by generating less anchors (thus decreasing the co...

The current research investigates the effect of incidental anger on anchoring bias. We hypothesized that feeling angry will make people less influenced by other‐provided anchors because of the moving against action tendency associated with anger. That is, individuals in an angry state will be likely to perceive a given anchor as a viable target for their desire to attack and actively seek out a...

In an age where news information is created by millions and consumed billions over social media ( SM ) every day, issues of biases, fake news, echo-chambers have dominated the corridors technology firms, corporations, policy makers, society. While multiple disciplines tried to tackle issue using their disciplinary lenses, there has, hitherto, been no integrative model that surface intricate, al...

Kinase anchoring has gained acceptance as a means to synchronize spatial and temporal aspects of cell signaling. A-kinase anchoring proteins (AKAPs) are a diverse group of functionally related proteins that target protein kinase A and other enzymes to coordinate a range of signaling events. Recent advances in this field have shown that incorporating phosphodiesterases into AKAP signaling comple...

Anchoring is the process of creating and maintaining the correspondence between symbols and percepts that refer to the same physical objects. Although this process must necessarily be present in any physically embedded system that includes a symbolic component (e.g., an autonomous robot), no systematic study of anchoring as a problem per se has been reported in the literature on intelligent sys...