Oral immunotherapy for food allergy has been the focus of a lot of attention recently. The patients have to eat allergenic food instead of eliminating it in this therapy and there is no established standard method yet. To promote clear understanding and improvement of oral immunotherapy, the present study using B10.A mice investigated the effect of multiple oral administration of a model antige...

The present study was investigated the effect of Houttuynia cordata THUNB water extract (HCWE) on mast cell-mediated anaphylactic reactions. The mast cell-mediated anaphylactic reaction is involved in many allergic diseases such as asthma and allergic rhinitis. HCWE has been used as a traditional medicine in Korea and is known to have an antioxidant and anti-cancer activities. However, its spec...

The skin irritant, xylol, when applied to the ears of sensitized and reinjected rabbits often causes a severe inflammation with the formation of crusts and destruction of tissue. Dry gangrene of the entire ear tip may result (Figs. 1, 2, and 3). The same agent, applied in the same dosage and in the same way, to the ears of (1) normal rabbits, (2) normal rabbits injected once with horse serum (s...

UNLABELLED : Ranitidine is a widely used drug and is known to be well tolerated. This case report illustrates a severe anaphylactic reaction after a single intravenous dose of 50 mgs of ranitidine and highlights this unusual but life threatening adverse reaction. THE PATIENT A 56 year old female with acute pancreatitis and a known allergy to metronidazole and buscopan developed an anaphylaxis...

To the Editor: We prepared a case report entitled ‘Suspected Anaphylactic Reaction Associated with a Microemulsion of Propofol during Anesthesia Induction’ (1). However, one reviewer commented that we should have considered midazolam (2), remifentanil (3), rocuronium (4), ephedrine (5), dexamethasone (6), epinephrine (7), poloxamer 188 (8), and polyethylene glycol (9) in addition to a microemul...